Temazepam or midazolam for night sedation. A double-blind study.
作者信息
Irjala J, Kanto J, Salonen M
机构信息
Department of Anaesthesiology, Turku Municipal Hospital, Finland.
出版信息
Anaesthesia. 1989 Aug;44(8):685-7. doi: 10.1111/j.1365-2044.1989.tb13596.x.
Abstract
The effects of oral temazepam (20 mg), oral midazolam (15 mg) and a placebo were compared for night sedation on the evening prior to surgery in a double-blind study. Patients in the placebo group had significantly worse sleep than those in the temazepam (p = 0.004) or midazolam groups (p = 0.04). There was no significant difference between the two drug groups, nor between the residual effects of the three treatments. Temazepam appears to be somewhat more effective than the ultrashort-acting midazolam in pre-operative transient insomnia.
摘要
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