小型日间手术中苯二氮䓬类药物的术前用药：口服咪达唑仑和替马西泮与安慰剂的比较。
Benzodiazepine premedication in minor day-case surgery: comparison of oral midazolam and temazepam with placebo.
作者信息
Hargreaves J
机构信息
Department of Anaesthesia, University Hospital of South Manchester.
出版信息
Br J Anaesth. 1988 Nov;61(5):611-6. doi: 10.1093/bja/61.5.611.
Ninety day-case or short stay patients were allocated to three groups in a double-blind study. The groups received oral midazolam 15 mg, oral temazepam 20 mg or placebo approximately 1 h before surgery. Midazolam was superior to temazepam regarding anxiolysis, sedation and amnesia, but temazepam was superior to placebo. However, delay in immediate and late recovery occurred significantly more often in the patients receiving midazolam than in those receiving temazepam or placebo.
在一项双盲研究中，将90名日间手术或短期住院患者分为三组。这些组在手术前约1小时分别接受口服咪达唑仑15毫克、口服替马西泮20毫克或安慰剂。在抗焦虑、镇静和遗忘方面，咪达唑仑优于替马西泮，但替马西泮优于安慰剂。然而，接受咪达唑仑的患者比接受替马西泮或安慰剂的患者更常出现即时和延迟恢复延迟的情况。
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