Lawal Taiwo Akeem, Adeleye Amos Olufemi
Division of Paediatric Surgery, Department of Surgery, College of Medicine, University of Ibadan, and University College Hospital, Ibadan, Nigeria.
Division of Neurological Surgery, Department of Surgery, College of Medicine, University of Ibadan, and Department of Neurological Surgery, University College Hospital, Ibadan, Nigeria.
Pan Afr Med J. 2014 Oct 1;19:113. doi: 10.11604/pamj.2014.19.113.4448. eCollection 2014.
In order to identify targets for primary preventive strategies, we explored possible predictors of periconceptional folic acid (pFA) intake in a Nigerian population of reproductively active women.
A cross sectional study of mothers attending immunization clinics at two hospitals was conducted between May and November 2012. Information obtained included sociodemographic and obstetric details and periconceptional usage of FA. Independent variables were analysed as predictors of pFA intake using chi-square statistical test and multinomial logistic regression.
The study involved 602 mothers aged 17 to 42 years; 23% had a university degree and 66% were in the working class. Preconceptional usage was proven in only 15 (2.5%). Periconceptional usage was more likely among professionals (X2=41.194, p<0.001), have university degree (X2=53.089, p<0.001), be primigravid (X2=18.415, p<0.001) and early antenatal clinic attendees (X2=355.9, p<0.001). Women were less likely to know that FA could prevent birth defects if in the working class (1.7% vs. 11.1%, X2=25.593, p<0.001), less educated (0.5 vs. 10.9%, X2=38.083, p<0.001) or booked late for antenatal care (2.0 vs. 5.9%, X2=5.767, p=0.016). The determinants of late commencement of FA were low social class (OR=4.29, 95% CI: 1.59, 11.31), lack of university education (OR=4.58, 95% CI: 3.06, 6.87) and late booking (OR=104.27, 95% CI: 53.09, 204.76).
In this population of reproductively active women, pFA intake and knowledge of its health benefits are poor amongst mothers--in working class, with limited education, and who present late for antenatal care.
为了确定初级预防策略的目标，我们在尼日利亚有生殖能力的女性人群中探索了围孕期叶酸（pFA）摄入的可能预测因素。
2012年5月至11月间，对在两家医院免疫接种门诊就诊的母亲进行了一项横断面研究。获取的信息包括社会人口统计学和产科详细信息以及围孕期叶酸使用情况。使用卡方统计检验和多项逻辑回归分析自变量作为pFA摄入的预测因素。
该研究纳入了602名年龄在17至42岁之间的母亲；23%拥有大学学位，66%属于工薪阶层。仅15名（2.5%）母亲在受孕前使用过叶酸。专业人员（X2 = 41.194，p < 0.001）、拥有大学学位者（X2 = 53.089，p < 0.001）、初产妇（X2 = 18.415，p < 0.001）以及早期参加产前检查者（X2 = 355.9，p < 0.001）围孕期使用叶酸的可能性更高。如果属于工薪阶层（1.7%对11.1%，X2 = 25.593，p < 0.001）、受教育程度较低（0.5%对10.9%，X2 = 38.083，p < 0.001）或产前检查预约较晚（2.0%对5.9%，X2 = 5.767，p = 0.016），女性知晓叶酸可预防出生缺陷的可能性较小。叶酸开始使用较晚的决定因素包括社会阶层较低（比值比[OR]=）4.29，95%置信区间[CI]：1.59，11.31）、缺乏大学教育（OR = 4.58，95% CI：3.06，6.87）以及预约较晚（OR = [104.27，95% CI：53.09，204.76]）。
在这群有生殖能力的女性中，工薪阶层、受教育程度有限且产前检查就诊较晚的母亲中，pFA摄入量及其对健康益处的知晓情况较差。
