From the School of Population and Public Health, Faculty of Medicine (J.J.C.), International Collaboration on Repair Discoveries (J.J.C., J.K.K., J.F.B.), and School of Kinesiology (J.K.K.), University of British Columbia, Vancouver; Simon Fraser University (F.M.W.), Burnaby; and British Columbia Institute of Technology (J.F.B.), Burnaby, Canada.
Neurology. 2015 Mar 31;84(13):1341-5. doi: 10.1212/WNL.0000000000001428. Epub 2015 Feb 27.
The objective of this study was to evaluate the association between chronic respiratory diseases (asthma and chronic obstructive pulmonary disease) and spinal cord injury (SCI) in a large representative sample.
Data were compiled from more than 60,000 individuals from the 2010 cycle of the cross-sectional Canadian Community Health Survey (CCHS). Multivariable logistic regression analysis was conducted to examine this relationship, adjusting for confounders, and using probability weighting to account for the CCHS sampling method.
After adjusting for age, sex, and smoking status, SCI was associated with a significant increased odds of asthma (adjusted odds ratio = 1.59 [95% confidence interval 1.11, 2.26]; p < 0.05) and chronic obstructive pulmonary disease (1.87 [1.20, 2.91]; p < 0.05).
These heightened odds highlight the exigent need for targeted interventions and prevention strategies for respiratory health among individuals with SCI.
本研究旨在评估在一个大的代表性样本中，慢性呼吸系统疾病（哮喘和慢性阻塞性肺疾病）与脊髓损伤（SCI）之间的关联。
数据来自于 2010 年加拿大社区健康调查（CCHS）的 6 万多人的数据。采用多变量逻辑回归分析来检验这种关系，调整了混杂因素，并使用概率加权来考虑 CCHS 的抽样方法。
在调整了年龄、性别和吸烟状况后，SCI 与哮喘（调整后的优势比=1.59[95%置信区间 1.11, 2.26]；p<0.05）和慢性阻塞性肺疾病（1.87[1.20, 2.91]；p<0.05）的显著增加几率相关。
这些增加的几率强调了针对 SCI 患者的呼吸健康的有针对性的干预和预防策略的迫切需要。
