Adamo Nicoletta, Baumeister Sarah, Hohmann Sarah, Wolf Isabella, Holz Nathalie, Boecker Regina, Laucht Manfred, Banaschewski Tobias, Brandeis Daniel
Department of Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim/Heidelberg University, Mannheim, Germany.
J Neural Transm (Vienna). 2015 Aug;122(8):1197-202. doi: 10.1007/s00702-015-1382-8. Epub 2015 Feb 28.
We assessed intra-individual variability of response times (RT) and single-trial P3 amplitudes following targets in healthy adults during a Flanker/NO-GO task. RT variability and variability of the neural responses coupled at the faster frequencies examined (0.07-0.17 Hz) at Pz, the target-P3 maxima, despite non-significant associations for overall variability (standard deviation, SD). Frequency-specific patterns of variability in the single-trial P3 may help to understand the neurophysiology of RT variability and its explanatory models of attention allocation deficits beyond intra-individual variability summary indices such as SD.
我们评估了健康成年人在侧翼/停止信号任务中对目标刺激的反应时间（RT）和单次试验P3波幅的个体内变异性。尽管总体变异性（标准差，SD）无显著相关性，但在Pz（目标P3波峰处）检测到的较快频率（0.07 - 0.17 Hz）下，RT变异性与神经反应变异性相关。单次试验P3波幅的频率特异性变异性模式可能有助于理解RT变异性的神经生理学及其注意力分配缺陷的解释模型，而不仅仅局限于诸如SD等个体内变异性汇总指标。
