Institut Pasteur, Genetics of Biofilms Unit, Department of Microbiology, 28 rue du Dr Roux, 75724 Paris cedex 15, France.
Cairo University, Faculty of Pharmacy, Pharmacognosy Department, Kasr El Aini Street, P.B. 11562, Cairo, Egypt.
FEMS Microbiol Rev. 2015 Mar;39(2):222-33. doi: 10.1093/femsre/fuu013. Epub 2015 Feb 2.
Bacterial interactions with neighboring microorganisms via production of small metabolites enable bacteria to respond and adapt to environmental changes. The study of intercellular interactions primarily focused on soluble metabolites, but bacteria also produce and release into their headspace a wide variety of volatile secondary metabolites, the ecological roles of which have generally been overlooked. However, bacterial volatile compounds are known to contribute to interkingdom interactions (plant, fungi and nematodes), and recent studies also identified their at-a-distance influence on bacterial behavior. The present review describes the biological roles of bacterial volatile compounds in inter- and intraspecies bacterial interactions, a new and yet unexplored research area, with potential clinical and industrial applications.
细菌通过产生小分子代谢物与邻近微生物相互作用，使细菌能够对环境变化做出反应和适应。细胞间相互作用的研究主要集中在可溶性代谢物上，但细菌也会产生并释放到其周围环境中各种各样的挥发性次生代谢物，其生态作用通常被忽视。然而，已知细菌挥发物有助于种间相互作用（植物、真菌和线虫），最近的研究也发现它们对细菌行为的远距离影响。本综述描述了细菌挥发物在种间和种内细菌相互作用中的生物学作用，这是一个新的、尚未探索的研究领域，具有潜在的临床和工业应用。
