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手臂孤立性丛状神经纤维瘤伴不寻常表现——1例罕见病例报告

Isolated plexiform neurofibroma of arm with unusual presentation - a rare case report.

作者信息

Mishra Pankaj Kumar, Dwivedi Rishi, Shrivastava Dinesh Chandra, Gaur Suresh Chandra

机构信息

Assistant Professor, Department of Orthopaedics, GMC and Hamidia Hospital Bhopal, India .

Senior Resident, Department of Orthopaedics, MLN Medical College Allahabad, UP, India .

出版信息

J Clin Diagn Res. 2015 Jan;9(1):RD03-4. doi: 10.7860/JCDR/2015/10530.5407. Epub 2015 Jan 1.

DOI:10.7860/JCDR/2015/10530.5407
PMID:25738048
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4347139/
Abstract

Plexiform neurofibroma (PNF) arises as a diffuse mass from nerve trunk and leads to overgrowth of cutis and subcutis structure. This is a case report of 20-year-old male, presented to our hospital with a giant ulcerated swelling over his left arm. Differential diagnosis of sarcoma, neurofibroma, hemangioma and angiolipoma was made but biopsy confirmed the diagnosis of plexiform neurofibroma. Isolated PNF with ulceration of overlying skin over arm is a rare presentation and here we are presenting it as a perusal of rare entity.

摘要

丛状神经纤维瘤(PNF)起源于神经干的弥漫性肿块,导致皮肤和皮下组织过度生长。这是一例20岁男性的病例报告,该患者因左臂巨大溃疡肿胀前来我院就诊。对肉瘤、神经纤维瘤、血管瘤和血管脂肪瘤进行了鉴别诊断,但活检确诊为丛状神经纤维瘤。孤立性臂部PNF伴覆盖皮肤溃疡是一种罕见的表现,在此我们将其作为罕见病例进行展示。

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本文引用的文献

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Plexiform neurofibromas in children with neurofibromatosis type 1: frequency and associated clinical deficits.丛状神经纤维瘤在 1 型神经纤维瘤病患儿中的发生频率及相关临床缺陷。
J Pediatr. 2011 Oct;159(4):652-5.e2. doi: 10.1016/j.jpeds.2011.04.008. Epub 2011 May 31.
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Prognostic signs in the surgical management of plexiform neurofibroma: the Children's Hospital of Philadelphia experience, 1974-1994.丛状神经纤维瘤手术治疗中的预后征象:费城儿童医院的经验,1974 - 1994年
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The diagnostic evaluation and multidisciplinary management of neurofibromatosis 1 and neurofibromatosis 2.神经纤维瘤病1型和神经纤维瘤病2型的诊断评估与多学科管理
JAMA. 1997 Jul 2;278(1):51-7.