Dierig Alexa, Frei Reno, Egli Adrian
From the *Division of Pediatric Infectious Diseases, University Children's Hospital Basel; †Clinical Microbiology, University Hospital Basel; and ‡Infection Biology, Department Biomedicine, University of Basel, Basel, Switzerland.
Pediatr Infect Dis J. 2015 Jan;34(1):97-9. doi: 10.1097/INF.0000000000000601.
Rapid identification of bacterial and fungal microorganisms is critical for early and targeted antimicrobial therapy. Conventional methods for bacterial identification are time consuming. Matrix assisted laser desorption/ionization-time of flight mass spectrometry (MALDI-TOF MS) has revolutionized the daily process of identification in modern microbiological laboratories. The technique and its multiple current and future applications will be discussed.
快速鉴定细菌和真菌微生物对于早期和针对性的抗菌治疗至关重要。传统的细菌鉴定方法耗时较长。基质辅助激光解吸/电离飞行时间质谱（MALDI-TOF MS）彻底改变了现代微生物实验室的日常鉴定流程。本文将讨论该技术及其当前和未来的多种应用。
