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来自一个地区胎盘组织样本库的起源故事。

Origin stories from a regional placenta tissue collection.

作者信息

Fannin Maria, Kent Julie

机构信息

School of Geographical Sciences, University of Bristol , Bristol , UK.

Centre for Health and Clinical Research, Department of Health & Applied Social Sciences, University of the West of England , Bristol , UK.

出版信息

New Genet Soc. 2015 Jan 2;34(1):25-51. doi: 10.1080/14636778.2014.999153. Epub 2015 Feb 4.

Abstract

Twenty-three years ago when women and their children were recruited to a longitudinal genetic epidemiological study during pregnancy, placentas were collected at birth. This paper explores the history of a regional placenta biobank and contemporary understandings of its value for the constitution of a research population. We draw on interviews with some of the mothers and those responsible for the establishment and curation of the placenta collection in order to explore the significance and meaning of the collection for them. Given its capacity to stand in for the study cohort of mothers and children, we argue that the material significance of the placenta biobank as a research tool seems far less important than the work it does in constituting a population. The stories about this collection may be understood within the wider context of developments in biobanking and the bioeconomy.

摘要

23年前,当女性及其子女在孕期被招募进一项纵向遗传流行病学研究时,胎盘在出生时被收集起来。本文探讨了一个地区胎盘生物样本库的历史以及对其在构成研究人群方面价值的当代理解。我们通过对一些母亲以及负责胎盘样本收集的建立和管理的人员进行访谈,来探究该样本收集对他们的意义。鉴于其能够代表母亲和孩子的研究队列,我们认为,胎盘生物样本库作为一种研究工具的物质意义似乎远不如它在构成一个人群方面所起的作用重要。关于这个样本收集的故事可以在生物样本库和生物经济发展的更广泛背景下得到理解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4d8/4337687/de715f5fc0d4/cngs-34-025-g001.jpg

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