Hønge Bo Langhoff, Hedegaard Sami Khatib, Cederstrøm Stephan, Nielsen Henrik
Infektionsmedicinsk Afdeling, Klinisk Medicin, Aalborg Universitetshospital, Hobrovej 18-22, 9000 Aalborg, Denmark.
Dan Med J. 2015 Mar;62(3).
Bites by the European adder, Vipera berus, may cause significant morbidity in bite victims, but this can be reduced through adequate treatment. Since the previous Danish study, a new treatment and a severity grading has been taken into use. The aims of this study were to review clinical cases after a bite from V. berus in The North Denmark Region and to evaluate the treatment given.
In the regional health-care database, we retrospectively identified all patients discharged with the International Classification of Diseases, 10th version (ICD-10) code "T 63.0 snake venom" in the 2007-2013 period. We reviewed patient records for patient demographics, clinical information and information about treatment.
During the study period, 76 patients were discharged from a hospital after being bitten by V. berus in The North Denmark Region. Envenomation grade 2 or 3 was seen in 61% of victims, and 21% of these were treated with antivenom. T-wave inversion was seen in 9% of the 54 patients in whom an electrocardiography had been performed. The median duration of admittance was 24 hours (mean 48 hours), and risk factors for a prolonged stay at the hospital were grade 2 or 3 envenomation, leukocytosis and moderate/massive oedema at the time of admittance.
Patients were admitted for a longer time than reported from a previous Danish study on adder bites, and many patients were possibly undertreated with regard to use of antivenom according to recommendations in recent guidelines. No adverse effects were noted due to administration of antivenom. T-wave inversion was observed more frequently than previously described.
not relevant.
The study was recorded with The North Denmark Region in accordance with a directive from the Danish Data Protection Agency.
被欧洲蝰蛇(Vipera berus)咬伤可能会给受害者带来严重的发病情况,但通过适当治疗可降低这种情况。自丹麦上一项研究以来,已采用了一种新的治疗方法和严重程度分级。本研究的目的是回顾丹麦北部地区被欧洲蝰蛇咬伤后的临床病例,并评估所给予的治疗。
在地区医疗保健数据库中,我们回顾性地确定了2007 - 2013年期间所有出院时国际疾病分类第10版(ICD - 10)编码为“T 63.0蛇毒”的患者。我们查阅了患者记录,以获取患者人口统计学信息、临床信息和治疗信息。
在研究期间,丹麦北部地区有76名患者被欧洲蝰蛇咬伤后出院。61%的受害者出现2级或3级中毒症状,其中21%接受了抗蛇毒血清治疗。在接受心电图检查的54名患者中,9%出现T波倒置。住院时间中位数为24小时(平均48小时),入院时2级或3级中毒、白细胞增多和中度/重度水肿是住院时间延长的危险因素。
与丹麦之前一项关于蝰蛇咬伤的研究报告相比,患者住院时间更长,并且根据近期指南的建议,许多患者在抗蛇毒血清的使用方面可能治疗不足。未观察到因使用抗蛇毒血清而产生的不良反应。T波倒置的观察频率比之前描述的更高。
不相关。
本研究已按照丹麦数据保护局的指令在丹麦北部地区进行记录。