Salakari Minna R J, Surakka Tiina, Nurminen Raija, Pylkkänen Liisa
Department of Public Health, University of Turku , Turku , Finland.
Acta Oncol. 2015 May;54(5):618-28. doi: 10.3109/0284186X.2014.996661. Epub 2015 Mar 9.
In parallel with the rising incidence of cancer and improved treatment, there is a continuous increase in the number of patients living with cancer as a chronic condition. Many cancer patients experience long-term disability and require continuous oncological treatment, care and support. The aim of this review is to evaluate the most recent data on the effects of rehabilitation among patients with advanced cancer.
A systematic review was conducted according to Fink's model. Only randomized controlled trials (RCTs) published in 2009-2014 were included. Medline/PubMed and Cochrane databases were searched; five groups of keywords were used. The articles were evaluated for outcome and methodological quality.
Thirteen RCTs (1169 participants) were evaluated. Most studies were on the effects of physical exercise in patients with advanced cancer (N = 7). Physical exercise was associated with a significant improvement in general wellbeing and quality of life. Rehabilitation had positive effects on fatigue, general condition, mood, and coping with cancer.
Rehabilitation is needed also among patients with advanced disease and in palliative care. Exercise improves physical performance and has positive effects on several other quality of life domains. More data and RCTs are needed, but current evidence gives an indication that rehabilitation is suitable and can be recommended for patients living with advanced cancer.
随着癌症发病率的上升和治疗方法的改进，作为慢性病的癌症存活患者数量持续增加。许多癌症患者经历长期残疾，需要持续的肿瘤治疗、护理和支持。本综述的目的是评估晚期癌症患者康复效果的最新数据。
根据芬克模型进行系统综述。仅纳入2009 - 2014年发表的随机对照试验（RCT）。检索了Medline/PubMed和Cochrane数据库；使用了五组关键词。对文章的结果和方法学质量进行评估。
评估了13项随机对照试验（1169名参与者）。大多数研究是关于体育锻炼对晚期癌症患者的影响（N = 7）。体育锻炼与总体幸福感和生活质量的显著改善相关。康复对疲劳、总体状况、情绪和应对癌症有积极影响。
晚期疾病患者和姑息治疗患者也需要康复。运动可改善身体机能，并对其他几个生活质量领域有积极影响。需要更多数据和随机对照试验，但目前的证据表明康复对晚期癌症患者是合适的且可推荐。
