低收入非裔美国青少年中感知到的歧视与心血管风险指标
Perceived discrimination and markers of cardiovascular risk among low-income African American youth.
作者信息
Goosby Bridget J, Malone Sarah, Richardson Elizabeth A, Cheadle Jacob E, Williams Deadric T
机构信息
Department of Sociology, University of Nebraska-Lincoln, 742 Oldfather Hall, Lincoln, Nebraska, 68588.
出版信息
Am J Hum Biol. 2015 Jul-Aug;27(4):546-52. doi: 10.1002/ajhb.22683. Epub 2015 Mar 7.
OBJECTIVES
Our study examines the relationship between perceived discrimination and levels of C-reactive protein and blood pressure in low-income youth ages 10-15 years old.
METHODS
Data were collected from 10 to 15 year old focal children and their mothers. Face-to-face interviews were implemented to collect data on stressors including experiences of everyday discrimination from youth. High sensitivity CRP in dried blood spot samples and diastolic and systolic blood pressure were also collected at the time of the interview.
RESULTS
Perceived discrimination among youth was significantly associated with higher levels of CRP, systolic, and diastolic blood pressure. CRP, systolic, and diastolic blood pressure remained significant after controlling for age-adjusted BMI, waist circumference, and other factors.
CONCLUSIONS
Discrimination is a salient risk factor for inflammation and cardiovascular health. Early life course inflammation and cardiovascular reactivity are important candidate pathways through which the repeated exposure to discrimination for minority group members contributes to racial and economic health inequities in adulthood.
目的
我们的研究考察了10至15岁低收入青少年中感知到的歧视与C反应蛋白水平及血压之间的关系。
方法
收集了10至15岁重点儿童及其母亲的数据。进行面对面访谈以收集关于压力源的数据，包括青少年日常遭受歧视的经历。在访谈时还收集了干血斑样本中的高敏C反应蛋白以及舒张压和收缩压。
结果
青少年中感知到的歧视与较高水平的C反应蛋白、收缩压和舒张压显著相关。在控制了年龄调整后的体重指数、腰围和其他因素后，C反应蛋白、收缩压和舒张压仍具有显著性。
结论
歧视是炎症和心血管健康的一个显著风险因素。早年生活中的炎症和心血管反应性是重要的候选途径，通过这些途径，少数群体成员反复遭受歧视会导致成年期的种族和经济健康不平等。
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