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母亲经历的种族歧视与拉丁裔青年研究中心中儿童心脏代谢结局的关系

Maternal experiences of ethnic discrimination and child cardiometabolic outcomes in the Study of Latino Youth.

机构信息

Department of Epidemiology and Biostatistics, University of Maryland, College Park.

Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY.

出版信息

Ann Epidemiol. 2019 Jun;34:52-57. doi: 10.1016/j.annepidem.2019.03.011. Epub 2019 Mar 28.

DOI:10.1016/j.annepidem.2019.03.011
PMID:31060896
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7282822/
Abstract

PURPOSE

Limited research has examined maternal experiences of racial/ethnic discrimination in relation to child cardiometabolic health. In this study, we investigated whether maternal experiences of ethnic discrimination were associated with cardiometabolic risk in Hispanic/Latino youth several years later.

METHODS

Our sample included 1146 youth (8-16 years) from the Study of Latino Youth (2012-2014), who were children of the Hispanic Community Health Study/Study of Latinos participants (2008-2011). We used regression models to examine the prospective associations between maternal report of ethnic discrimination in relation to her child's body mass index (BMI) z-score, metabolic syndrome score (MetS), and high sensitivity C-reactive protein (hsCRP) levels 2 years later.

RESULTS

Maternal ethnic discrimination was associated with youth hsCRP, but not BMI or MetS (P-values >.05). Adjusting for age, nativity, and national background, maternal ethnic discrimination was associated with higher (log) hsCRP levels (β = 0.18, 95% CI = 0.04 to 0.32) in children. This association was robust to adjustment for maternal and household characteristics (β = 0.17, 95% CI = 0.04 to 0.31), as well as maternal depression and maternal BMI.

CONCLUSIONS

Maternal ethnic discrimination is associated with inflammation among Hispanic/Latino youth, and not BMI z-score or MetS. Studies are needed to address temporality and pathways.

摘要

目的

关于种族/民族歧视与儿童心脏代谢健康的关系,研究有限。本研究调查了多年后,西班牙裔/拉丁裔青年的母亲经历种族歧视是否与心脏代谢风险有关。

方法

我们的样本包括来自拉丁裔青年研究(2012-2014 年)的 1146 名青少年(8-16 岁),他们是西班牙裔社区健康研究/拉丁裔研究参与者(2008-2011 年)的孩子。我们使用回归模型来检验母亲报告的种族歧视与孩子的体重指数(BMI)z 分数、代谢综合征评分(MetS)和 2 年后高敏 C 反应蛋白(hsCRP)水平之间的前瞻性关联。

结果

母亲的种族歧视与青少年的 hsCRP 有关,但与 BMI 或 MetS 无关(P 值>.05)。调整年龄、出生国和民族背景后,母亲的种族歧视与儿童更高的(对数)hsCRP 水平相关(β=0.18,95%CI=0.04 至 0.32)。该关联在调整母亲和家庭特征(β=0.17,95%CI=0.04 至 0.31)以及母亲抑郁和母亲 BMI 后仍然稳健。

结论

母亲的种族歧视与西班牙裔/拉丁裔青少年的炎症有关,而与 BMI z 分数或 MetS 无关。需要进一步研究以明确时间顺序和相关途径。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bc6/7282822/bae816aa148b/nihms-1593681-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bc6/7282822/bae816aa148b/nihms-1593681-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bc6/7282822/bae816aa148b/nihms-1593681-f0001.jpg

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