Department of Epidemiology and Biostatistics, University of Maryland, College Park.
Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY.
Ann Epidemiol. 2019 Jun;34:52-57. doi: 10.1016/j.annepidem.2019.03.011. Epub 2019 Mar 28.
Limited research has examined maternal experiences of racial/ethnic discrimination in relation to child cardiometabolic health. In this study, we investigated whether maternal experiences of ethnic discrimination were associated with cardiometabolic risk in Hispanic/Latino youth several years later.
Our sample included 1146 youth (8-16 years) from the Study of Latino Youth (2012-2014), who were children of the Hispanic Community Health Study/Study of Latinos participants (2008-2011). We used regression models to examine the prospective associations between maternal report of ethnic discrimination in relation to her child's body mass index (BMI) z-score, metabolic syndrome score (MetS), and high sensitivity C-reactive protein (hsCRP) levels 2 years later.
Maternal ethnic discrimination was associated with youth hsCRP, but not BMI or MetS (P-values >.05). Adjusting for age, nativity, and national background, maternal ethnic discrimination was associated with higher (log) hsCRP levels (β = 0.18, 95% CI = 0.04 to 0.32) in children. This association was robust to adjustment for maternal and household characteristics (β = 0.17, 95% CI = 0.04 to 0.31), as well as maternal depression and maternal BMI.
Maternal ethnic discrimination is associated with inflammation among Hispanic/Latino youth, and not BMI z-score or MetS. Studies are needed to address temporality and pathways.
关于种族/民族歧视与儿童心脏代谢健康的关系,研究有限。本研究调查了多年后,西班牙裔/拉丁裔青年的母亲经历种族歧视是否与心脏代谢风险有关。
我们的样本包括来自拉丁裔青年研究(2012-2014 年)的 1146 名青少年(8-16 岁),他们是西班牙裔社区健康研究/拉丁裔研究参与者(2008-2011 年)的孩子。我们使用回归模型来检验母亲报告的种族歧视与孩子的体重指数(BMI)z 分数、代谢综合征评分(MetS)和 2 年后高敏 C 反应蛋白(hsCRP)水平之间的前瞻性关联。
母亲的种族歧视与青少年的 hsCRP 有关,但与 BMI 或 MetS 无关(P 值>.05)。调整年龄、出生国和民族背景后,母亲的种族歧视与儿童更高的(对数)hsCRP 水平相关(β=0.18,95%CI=0.04 至 0.32)。该关联在调整母亲和家庭特征(β=0.17,95%CI=0.04 至 0.31)以及母亲抑郁和母亲 BMI 后仍然稳健。
母亲的种族歧视与西班牙裔/拉丁裔青少年的炎症有关,而与 BMI z 分数或 MetS 无关。需要进一步研究以明确时间顺序和相关途径。