Schut C, Muhl S, Reinisch K, Claßen A, Jäger R, Gieler U, Kupfer J
Institute of Medical Psychology, University of Giessen, Giessen, Germany.
University Clinics for Dermatology and Allergology, Giessen, Germany.
Int J Behav Med. 2015 Dec;22(6):726-34. doi: 10.1007/s12529-015-9471-5.
Psoriasis (PS) is a frequent skin disease accompanied by itch, a symptom that has been shown to be related to depression and self-consciousness. PS patients describe themselves as more agreeable than healthy controls (HC), a trait that might be protective against impulsive scratching.
This study is the first to analyze the relationship between agreeableness and induced scratching and between depression, self-consciousness, and induced itch in PS patients.
Twenty-four PS patients and 24 HC were shown two videos: an itch-inducing experimental video (EV) and a non-itch-inducing control video (CV). Induced itch/scratching was determined by calculating the difference in itch intensity/number of scratch movements between EV and CV. Validated questionnaires were used to measure agreeableness, depression, and self-consciousness.
In accordance with our hypothesis, in PS patients, public self-consciousness was significantly positively associated with induced itch (r = 0.564; p < 0.001), and agreeableness was significantly negatively associated with induced scratching (r = -0.444; p < 0.05). In HC, the relationship between public self-consciousness and induced itch and between agreeableness and induced scratching were positive, but not significant.
This study showed distinct findings for PS patients and HC regarding the relationship between agreeableness and induced scratching. The relationship between public self-consciousness and induced itch was positive in both groups. The distinct finding regarding agreeableness supports the idea that scoring low on this scale might be a protective factor for scratching in PS patients. Future research should investigate mediating factors of the outlined relationships.
银屑病（PS）是一种常见的皮肤病，伴有瘙痒症状，该症状已被证明与抑郁和自我意识有关。银屑病患者将自己描述为比健康对照者（HC）更随和，这一特质可能对冲动性搔抓有保护作用。
本研究首次分析了银屑病患者随和性与诱发搔抓之间以及抑郁、自我意识与诱发瘙痒之间的关系。
向24名银屑病患者和24名健康对照者展示两段视频：一段诱发瘙痒的实验视频（EV）和一段不诱发瘙痒的对照视频（CV）。通过计算EV和CV之间瘙痒强度/搔抓动作次数的差异来确定诱发的瘙痒/搔抓情况。使用经过验证的问卷来测量随和性、抑郁和自我意识。
与我们的假设一致，在银屑病患者中，公众自我意识与诱发瘙痒显著正相关（r = 0.564；p < 0.001），随和性与诱发搔抓显著负相关（r = -0.444；p < 0.05）。在健康对照者中，公众自我意识与诱发瘙痒之间以及随和性与诱发搔抓之间的关系呈正相关，但不显著。
本研究显示了银屑病患者和健康对照者在随和性与诱发搔抓关系方面的不同结果。两组中公众自我意识与诱发瘙痒之间的关系均为正相关。关于随和性的不同结果支持了在该量表上得分低可能是银屑病患者搔抓保护因素的观点。未来的研究应调查上述关系的中介因素。
