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转移性腺癌大量浸润肝脏：急性肝衰竭的罕见病因。

Massive infiltration of liver by metastatic adenocarcinoma: a rare cause of acute hepatic failure.

作者信息

Varghese Joy, Jayanthi Venkataraman, Patra Susma, Rela Mohamed

机构信息

Departments of Hepatology & Liver Transplantation, Global Hospitals & Health City, Chennai 600100, Tamilnadu, India.

Department of Pathology, Global Hospitals & Health City, Chennai 600100, Tamilnadu, India.

出版信息

J Clin Exp Hepatol. 2012 Sep;2(3):286-8. doi: 10.1016/j.jceh.2012.06.002. Epub 2012 Sep 21.

DOI:10.1016/j.jceh.2012.06.002
PMID:25755446
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3940235/
Abstract

Acute liver cell failure can occur by diffuse infiltration of malignant cells in liver parenchyma. The malignant cells might be either primary hepatocellular carcinoma or metastatic liver disease. Mostly, CT abdomen with intravenous contrast fails to detect liver malignancy. We report a case of liver metastasis masquerading as fulminant hepatic failure.

摘要

急性肝细胞衰竭可因恶性细胞在肝实质内弥漫浸润而发生。这些恶性细胞可能是原发性肝细胞癌或转移性肝病。大多数情况下，腹部CT增强扫描无法检测出肝脏恶性肿瘤。我们报告一例伪装成暴发性肝衰竭的肝转移病例。

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本文引用的文献

1
Diffuse liver metastasis of small cell lung cancer causing marked hepatomegaly and fulminant hepatic failure.小细胞肺癌的弥漫性肝转移导致显著肝肿大和暴发性肝衰竭。
Intern Med. 2010;49(14):1383-6. doi: 10.2169/internalmedicine.49.3296. Epub 2010 Jul 15.
2
[Fulminant non-Hodgkin lymphoma presenting as lactic acidosis and acute liver failure: case report and literature review].[以乳酸酸中毒和急性肝衰竭为表现的暴发性非霍奇金淋巴瘤：病例报告及文献综述]
Acta Gastroenterol Latinoam. 2009 Jun;39(2):129-34.
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Metastatic prostatic carcinoma presenting as fulminant hepatic failure.以暴发性肝衰竭为表现的转移性前列腺癌。
South Med J. 2008 Oct;101(10):1049-50. doi: 10.1097/SMJ.0b013e31817c74c3.
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Diffuse malignant infiltration of the liver manifesting as a case of acute liver failure.肝脏弥漫性恶性浸润表现为急性肝衰竭病例。
Nat Clin Pract Gastroenterol Hepatol. 2008 Jul;5(7):405-8. doi: 10.1038/ncpgasthep1154. Epub 2008 Jun 3.
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[Fulminant liver failure associated with T-cell non-Hodgkin's lymphoma and hepatitis C virus: a case report].[与T细胞非霍奇金淋巴瘤及丙型肝炎病毒相关的暴发性肝衰竭：一例报告]
Gastroenterol Hepatol. 2006 Nov;29(9):542-5. doi: 10.1157/13094349.
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[Acute hepatic failure as a presenting sign of breast carcinoma].[急性肝衰竭作为乳腺癌的首发症状]
Harefuah. 2005 Dec;144(12):836-8, 911.
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An unusual presentation of hepatocellular carcinoma: case report and review.肝细胞癌的一种不寻常表现：病例报告及文献复习
Conn Med. 2005 Mar;69(3):133-8.
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Arch Pathol Lab Med. 2004 Dec;128(12):1418-23. doi: 10.5858/2004-128-1418-RODIHM.
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Severe lactic acidosis in a 14-year-old female with metastatic undifferentiated carcinoma of unknown primary.一名14岁患有原发性不明的转移性未分化癌的女性发生严重乳酸性酸中毒。
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