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特比萘芬所致肝损伤:一例报告

Terbinafine induced liver injury: a case report.

作者信息

Choudhary Narendra S, Kotecha Hardik, Saraf Neeraj, Gautam Dheeraj, Saigal Sanjiv

机构信息

Institute of Liver Transplantation and Regenerative Medicine, Medanta, The Medicity, Sector 38, Gurgaon, Haryana, India.

Institute of Digestive and Hepatobiliary Sciences, Medanta, The Medicity, Sector 38, Gurgaon, Haryana, India.

出版信息

J Clin Exp Hepatol. 2014 Sep;4(3):264-5. doi: 10.1016/j.jceh.2014.03.040. Epub 2014 Apr 3.

Abstract

Drug induced liver injury (DILI) is a cause of significant morbidity; timely diagnosis is important and requires a high index of suspicion. Terbinafine induced liver injury is rare. We report a case of Terbinafine induced hepatitis-cholestatic injury. The patient had a prolonged recovery phase lasting 3 months after discontinuation of drug.

摘要

药物性肝损伤(DILI)是导致严重发病的一个原因;及时诊断很重要,且需要高度的怀疑指数。特比萘芬所致肝损伤较为罕见。我们报告一例特比萘芬所致的肝炎-胆汁淤积性损伤病例。该患者在停药后有一个持续3个月的漫长恢复期。

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引用本文的文献

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本文引用的文献

1
Case definition and phenotype standardization in drug-induced liver injury.药物性肝损伤的病例定义和表型标准化。
Clin Pharmacol Ther. 2011 Jun;89(6):806-15. doi: 10.1038/clpt.2011.58. Epub 2011 May 4.
6
Ursodeoxycholic acid for terbinafine-induced toxic hepatitis.熊去氧胆酸治疗特比萘芬所致中毒性肝炎。
Ann Pharmacother. 2004 Jun;38(6):1088-9. doi: 10.1345/aph.1D420. Epub 2004 Apr 30.

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