应对印度的乙肝疾病负担
Tackling the Hepatitis B Disease Burden in India.
作者信息
Puri Pankaj
机构信息
Department of Gastroenterology, Army Hospital (Research & Referral), Dhaula Kuan, New Delhi 110010, India.
出版信息
J Clin Exp Hepatol. 2014 Dec;4(4):312-9. doi: 10.1016/j.jceh.2014.12.004. Epub 2014 Dec 15.
Abstract
Globally, approximately 240 people have been infected worldwide with hepatitis B Virus (HBV). India has approximately HBV carrier rate of 3.0% with a high prevalence rate in the tribal population. With a population of more than 1.25 billion, India has more than 37 million HBV carriers and contributes a large proportion of this HBV burden. While horizontal transmission in childhood appears to be a major route of transmission, the role of vertical transmission is probably underestimated. Blood transfusion and unsafe therapeutic injections continue to be important modes of transmission of HBV. There is a need for large field studies to better understand HBV epidemiology and identify high prevalence areas, and public health measures to prevent disease transmission and decrease the burden of the disease.
摘要
全球范围内，约有240人感染了乙肝病毒（HBV）。印度的HBV携带率约为3.0%，部落人口中的患病率较高。印度人口超过12.5亿，HBV携带者超过3700万，占HBV负担的很大一部分。虽然儿童期的水平传播似乎是主要传播途径，但垂直传播的作用可能被低估了。输血和不安全的治疗性注射仍然是HBV的重要传播方式。需要进行大规模的现场研究，以更好地了解HBV流行病学并确定高流行地区，还需要采取公共卫生措施来预防疾病传播并减轻疾病负担。
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