Tajima Shogo, Waki Michihiko, Ohata Akihiko, Koda Kenji, Maruyama Yasuhiko
Department of Pathology, Shizuoka Saiseikai General Hospital Shizuoka, Japan ; Department of Pathology, Fujieda Municipal General Hospital Shizuoka, Japan.
Department of Cell Biology and Anatomy, Hamamatsu University School of Medicine Shizuoka, Japan.
Int J Clin Exp Pathol. 2015 Jan 1;8(1):1013-8. eCollection 2015.
Xanthogranulomatous gastritis (XGG) is a rarely encountered condition, and its causative mechanism is still unclear. Given that some types of xanthogranulomatous inflammation (XGI) are associated with pathogens, infection should be considered as a possible cause of XGG. Herein, we report a case of an 86-year-old woman presenting with a large, bleeding lesion resembling a submucosal tumor. Distal gastrectomy was performed, and the surgically resected specimen revealed a mass measuring 6 × 4.5 × 3 cm and appearing yellowish on the cut surface. Histopathological examination revealed a few Actinomyces "sulfur granules" and cellular composition characteristic of XGI, supporting a diagnosis of XGG associated with actinomycosis. Gastric actinomycosis is a rare condition and has not previously been reported in association with XGG, although rare cases of XGI associated with actinomycosis have been documented in other organs.
黄色肉芽肿性胃炎（XGG）是一种罕见疾病，其致病机制尚不清楚。鉴于某些类型的黄色肉芽肿性炎症（XGI）与病原体有关，感染应被视为XGG的一个可能病因。在此，我们报告一例86岁女性患者，其表现为一个类似黏膜下肿瘤的巨大出血性病变。行远端胃切除术，手术切除标本显示一个大小为6×4.5×3 cm的肿物，切面呈淡黄色。组织病理学检查发现少量放线菌“硫磺颗粒”以及XGI的细胞组成特征，支持诊断为与放线菌病相关的XGG。胃放线菌病是一种罕见疾病，此前虽有其他器官与放线菌病相关的罕见XGI病例报道，但胃放线菌病与XGG相关此前尚未见报道。
