从阿尔及利亚一名儿童脑脊液中分离出的产KPC肺炎克雷伯菌ST512的出现。
Emergence of KPC-producing Klebsiella pneumoniae ST512 isolated from cerebrospinal fluid of a child in Algeria.
作者信息
Bakour S, Sahli F, Touati A, Rolain J-M
机构信息
Laboratoire d'Ecologie Microbienne, Université de Bejaia, Bejaia, Algeria ; Unité de recherche sur les maladies infectieuses et tropicales émergentes (URMITE), IHU Méditerranée Infection, Faculté de Médecine et de Pharmacie, Aix-Marseille-Université, Marseille, France.
Laboratoire de Microbiologie, CHU de Sétif, Algeria.
出版信息
New Microbes New Infect. 2014 Nov 8;3:34-6. doi: 10.1016/j.nmni.2014.09.001. eCollection 2015 Jan.
Abstract
We report class A carbapenemase (KPC)-3-producing Klebsiella pneumoniae meningitis in a 6-month-old child in Algeria. Multilocus sequence typing showed that the sequence type obtained corresponded to ST512, an allelic single-locus variant of the pandemic ST258 widely distributed in KPC producers from Europe. To our knowledge, this is the first report of KPC-3-producing K. pneumoniae ST512 in a North African country.
摘要
我们报告了在阿尔及利亚一名6个月大儿童中发生的产A类碳青霉烯酶（KPC）-3的肺炎克雷伯菌脑膜炎。多位点序列分型显示，所获得的序列类型对应于ST512，它是广泛分布于欧洲产KPC菌株中的大流行ST258的等位单基因变体。据我们所知，这是北非国家首次报告产KPC-3的肺炎克雷伯菌ST512。
相似文献
1
Emergence of KPC-producing Klebsiella pneumoniae ST512 isolated from cerebrospinal fluid of a child in Algeria.
New Microbes New Infect. 2014 Nov 8;3:34-6. doi: 10.1016/j.nmni.2014.09.001. eCollection 2015 Jan.
2
Molecular epidemiology of carbapenem resistant Enterobacteriaceae in Valle d'Aosta region, Italy, shows the emergence of KPC-2 producing Klebsiella pneumoniae clonal complex 101 (ST101 and ST1789).
BMC Microbiol. 2015 Nov 9;15(1):260. doi: 10.1186/s12866-015-0597-z.
3
Molecular epidemiology of KPC-producing Klebsiella pneumoniae from invasive infections in Italy: increasing diversity with predominance of the ST512 clade II sublineage.
J Antimicrob Chemother. 2016 Dec;71(12):3386-3391. doi: 10.1093/jac/dkw337. Epub 2016 Sep 1.
4
Emergence of Carbapenemase Producing Klebsiella Pneumonia and Spread of KPC-2 and KPC-17 in Taiwan: A Nationwide Study from 2011 to 2013.
PLoS One. 2015 Sep 18;10(9):e0138471. doi: 10.1371/journal.pone.0138471. eCollection 2015.
5
Multiregional dissemination of KPC-producing Klebsiella pneumoniae ST258/ST512 genotypes in Poland, 2010-14.
J Antimicrob Chemother. 2017 Jun 1;72(6):1610-1616. doi: 10.1093/jac/dkx054.
6
Characterisation of the first ongoing outbreak due to KPC-3-producing Klebsiella pneumoniae (ST512) in Spain.
Int J Antimicrob Agents. 2014 Dec;44(6):538-40. doi: 10.1016/j.ijantimicag.2014.08.006. Epub 2014 Sep 26.
7
Multifocal diffusion of a KPC-3 producing ST512 K. pneumoniae clone in Northern Italy.
New Microbiol. 2013 Jan;36(1):109-10. Epub 2013 Jan 1.
8
Multiclonal dispersal of KPC genes following the emergence of non-ST258 KPC-producing Klebsiella pneumoniae clones in Madrid, Spain.
J Antimicrob Chemother. 2013 Nov;68(11):2487-92. doi: 10.1093/jac/dkt237. Epub 2013 Jun 20.
9
Emergence of clonally related Klebsiella pneumoniae isolates of sequence type 258 producing plasmid-mediated KPC carbapenemase in Norway and Sweden.
J Antimicrob Chemother. 2009 Apr;63(4):654-8. doi: 10.1093/jac/dkp018. Epub 2009 Feb 13.
10
Changing epidemiology of KPC-producing Klebsiella pneumoniae in Argentina: Emergence of hypermucoviscous ST25 and high-risk clone ST307.
J Glob Antimicrob Resist. 2019 Sep;18:238-242. doi: 10.1016/j.jgar.2019.06.005. Epub 2019 Jun 13.
引用本文的文献
1
Phenotypic and Genotypic Characterization of ESBL-, AmpC-, and Carbapenemase-Producing and High-Risk CC131, with the First Report of ST1193 as a Causative Agent of Urinary Tract Infections in Human Patients in Algeria.
Antibiotics (Basel). 2025 May 9;14(5):485. doi: 10.3390/antibiotics14050485.
2
Epidemiological and genetic characteristics of clinical carbapenemase-producing Enterobacterales isolates from Batna hospitals in Algeria.
BMC Infect Dis. 2024 Dec 18;24(1):1439. doi: 10.1186/s12879-024-10300-8.
3
Risk factors associated with colistin resistance in carbapenemase-producing Enterobacterales: a multicenter study from a low-income country.
Ann Clin Microbiol Antimicrob. 2023 Aug 2;22(1):64. doi: 10.1186/s12941-023-00609-8.
4
Isolation, Genomic Analysis, and Preliminary Application of a Bovine Bacteriophage vB_Kpn_B01.
Front Vet Sci. 2021 Sep 3;8:622049. doi: 10.3389/fvets.2021.622049. eCollection 2021.
5
Molecular Epidemiological Insights into Colistin-Resistant and Carbapenemases-Producing Clinical Isolates.
Infect Drug Resist. 2019 Dec 3;12:3783-3795. doi: 10.2147/IDR.S226416. eCollection 2019.
6
Role of Institut Hospitalo-Universitaire Méditerranée Infection in the surveillance of resistance to antibiotics and training of students in the Mediterranean basin and in African countries.
New Microbes New Infect. 2018 Jun 14;26:S52-S64. doi: 10.1016/j.nmni.2018.06.001. eCollection 2018 Nov.
7
Deciphering Heteroresistance to Colistin in a Klebsiella pneumoniae Isolate from Marseille, France.
Antimicrob Agents Chemother. 2017 May 24;61(6). doi: 10.1128/AAC.00356-17. Print 2017 Jun.
8
Epidemiology of Carbapenem Resistant Klebsiella pneumoniae Infections in Mediterranean Countries.
Mediterr J Hematol Infect Dis. 2016 Jul 1;8(1):e2016032. doi: 10.4084/MJHID.2016.032. eCollection 2016.
9
Global Dissemination of Carbapenemase-Producing Klebsiella pneumoniae: Epidemiology, Genetic Context, Treatment Options, and Detection Methods.
Front Microbiol. 2016 Jun 13;7:895. doi: 10.3389/fmicb.2016.00895. eCollection 2016.
10
First report of NDM-5-producing Escherichia coli ST1284 isolated from dog in Bejaia, Algeria.
New Microbes New Infect. 2015 Sep 10;8:17-8. doi: 10.1016/j.nmni.2015.09.002. eCollection 2015 Nov.
本文引用的文献
1
Carbapenemases in Enterobacteriaceae: the magnitude of a worldwide concern.
Clin Microbiol Infect. 2014 Sep;20(9):819-20. doi: 10.1111/1469-0691.12737. Epub 2014 Jul 29.
2
Epidemiology of carbapenemase-producing Enterobacteriaceae and Acinetobacter baumannii in Mediterranean countries.
Biomed Res Int. 2014;2014:305784. doi: 10.1155/2014/305784. Epub 2014 May 13.
3
Carbapenemase-producing Klebsiella pneumoniae bloodstream infections: lowering mortality by antibiotic combination schemes and the role of carbapenems.
Antimicrob Agents Chemother. 2014;58(4):2322-8. doi: 10.1128/AAC.02166-13. Epub 2014 Feb 10.
4
Limiting and controlling carbapenem-resistant Klebsiella pneumoniae.
Infect Drug Resist. 2013 Dec 10;7:9-14. doi: 10.2147/IDR.S44358.
5
Clonal dissemination of Klebsiella pneumoniae ST512 carrying blaKPC-3 in a hospital in southern Italy.
APMIS. 2014 Jan;122(1):42-6. doi: 10.1111/apm.12097. Epub 2013 May 8.
6
Prevalence of carbapenemase-encoding genes including New Delhi metallo-β-lactamase in Acinetobacter species, Algeria.
Int J Infect Dis. 2013 Sep;17(9):e739-43. doi: 10.1016/j.ijid.2013.02.024. Epub 2013 Apr 16.
7
Rapid detection of carbapenemase-producing Enterobacteriaceae.
Emerg Infect Dis. 2012 Sep;18(9):1503-7. doi: 10.3201/eid1809.120355.
8
A carbapenem-resistant Klebsiella pneumoniae epidemic clone in Jerusalem: sequence type 512 carrying a plasmid encoding aac(6')-Ib.
J Antimicrob Chemother. 2012 Apr;67(4):898-901. doi: 10.1093/jac/dkr552. Epub 2012 Jan 26.
9
Emergence of New Delhi metallo-beta-lactamase (NDM-1) and Klebsiella pneumoniae carbapenemase (KPC-2) in South Africa.
J Clin Microbiol. 2012 Feb;50(2):525-7. doi: 10.1128/JCM.05956-11. Epub 2011 Nov 23.
10
Novel VIM metallo-beta-lactamase variant from clinical isolates of Enterobacteriaceae from Algeria.
Antimicrob Agents Chemother. 2010 Jan;54(1):466-70. doi: 10.1128/AAC.00017-09. Epub 2009 Nov 9.
Zotero 插件