Proimos Efklidis K, Kiagiadaki Devora E, Chimona Theognosia S, Seferlis Fokion G, Maroudias Nicolas J, Papadakis Chariton E
Rhinology. 2015 Mar;53(1):66-74. doi: 10.4193/Rhino13.203.
Chronic rhinosinusitis (CRS) is a disease with increasing incidence, characterized by persistent symptoms and negative impact on patient`s quality of life. Nasal inspiratory peak flow (NIPF) and acoustic rhinometry (AR) were studied and compared as assessment tools for CRS with or without nasal polyps (NP), as well as, in follow up monitoring of conservative medical treatment.
Seventy-eight patients were prospectively studied. Objective assessment included NIPF and AR at baseline and at 4 and 8 weeks after onset medical treatment. Measurements were studied in correlation with Sinonasal Outcome Test-22 (SNOT-22) questionnaire, Visual Analogue Scale (VAS) and endoscopic appearance score (EAS).
Both NIPF and AR improved significantly, after medical treatment. NIPF score reflected CRS symptoms` improvement according to SNOT-22 total score at the end of treatment protocol, showing moderate to strong correlation with nasal obstruction VAS grading during the treatment period. AR measures were associated with EAS in all sets of examinations and correlated moderately with VAS scoring at 8 weeks.
NIPF and AR were proven to be promising methods for objective evaluation and monitoring of nasal obstruction based on different aspects of nasal physiology in patients with CRS.
慢性鼻-鼻窦炎（CRS）是一种发病率不断上升的疾病，其特征为症状持续且对患者生活质量产生负面影响。对鼻吸气峰流量（NIPF）和声反射鼻测量法（AR）进行了研究和比较，以作为CRS伴或不伴鼻息肉（NP）的评估工具，以及用于保守药物治疗的随访监测。
对78例患者进行前瞻性研究。客观评估包括在基线以及药物治疗开始后4周和8周时的NIPF和AR。研究测量结果与鼻窦结局测试-22（SNOT-22）问卷、视觉模拟量表（VAS）和内镜表现评分（EAS）之间的相关性。
药物治疗后，NIPF和AR均有显著改善。根据治疗方案结束时的SNOT-22总分，NIPF评分反映了CRS症状的改善情况，在治疗期间与鼻塞VAS分级呈中度至强相关性。在所有检查组中，AR测量结果均与EAS相关，且在8周时与VAS评分呈中度相关。
基于CRS患者鼻生理的不同方面，NIPF和AR被证明是用于客观评估和监测鼻塞的有前景的方法。
