Poeggel Sven, Duraibabu Dineshbabu, Tosi Daniele, Leen Gabriel, Lewis Elfed, McGrath Deirdre, Fusco Ferdinando, Sannino Simone, Lupoli Laura, Ippolito Juliet, Mirone Vincenzo
University of Limerick, Department of Electronic and Computer Engineering, Optical Fibre Sensors Research Centre, Main-building C2-051, Limerick 00000, Ireland.
University of Limerick, Department of Electronic and Computer Engineering, Optical Fibre Sensors Research Centre, Main-building C2-051, Limerick 00000, IrelandbNazarbayev University, School of Engineering, Electrical & Electronic Engineering, 53 Kabanbay.
J Biomed Opt. 2015 Mar;20(3):037005. doi: 10.1117/1.JBO.20.3.037005.
Urodynamic analysis is the predominant method for evaluating dysfunctions in the lower urinary tract. The exam measures the pressure during the filling and voiding process of the bladder and is mainly interested in the contraction of the bladder muscles. The data arising out of these pressure measurements enables the urologist to arrive at a precise diagnosis and prescribe an adequate treatment. A technique based on two optical fiber pressure and temperature sensors with a resolution of better than 0.1 cm H₂O (∼10 Pa), a stability better than 1 cm H₂O/hour, and a diameter of 0.2 mm in a miniature catheter with a diameter of only 5 Fr (1.67 mm), was used. This technique was tested in vivo on four patients with a real-time urodynamic measurement system. The optical system presented showed a very good correlation to two commercially available medical reference sensors. Furthermore, the optical urodynamic system demonstrated a higher dynamic and better sensitivity to detect small obstructions than both pre-existing medical systems currently in use in the urodynamic field.
尿动力学分析是评估下尿路功能障碍的主要方法。该检查测量膀胱充盈和排尿过程中的压力,主要关注膀胱肌肉的收缩情况。这些压力测量产生的数据使泌尿科医生能够做出准确诊断并开出适当的治疗方案。采用了一种基于两个光纤压力和温度传感器的技术,其分辨率优于0.1 cmH₂O(约10 Pa),稳定性优于1 cmH₂O/小时,且在直径仅为5 Fr(1.67 mm)的微型导管中的直径为0.2 mm。该技术在四名患者身上通过实时尿动力学测量系统进行了体内测试。所展示的光学系统与两个市售的医学参考传感器具有非常好的相关性。此外,与目前尿动力学领域使用的两种现有医学系统相比,光学尿动力学系统在检测小梗阻方面表现出更高的动态性和更好的灵敏度。