Scruton M W
Sterilization Research & Development Unit, PHLS Centre for Microbiology & Research, Salisbury, Wiltshire, UK.
J Hosp Infect. 1989 Nov;14(4):339-50. doi: 10.1016/0195-6701(89)90074-1.
The presence of air in an autoclave chamber and load is generally considered to reduce the lethal effect of the process on bacterial spores. In this study, the heat inactivation of spores of Bacillus stearothermophilus (NCIB 8224) was measured in the presence and absence of air at 100% relative humidity. The results confirm that air significantly enhances the lethality of moist-heat on this strain of B. stearothermophilus.
通常认为，高压灭菌器腔室及灭菌物品中有空气会降低该过程对细菌芽孢的致死效果。在本研究中，测定了嗜热脂肪芽孢杆菌（NCIB 8224）芽孢在相对湿度100%且有空气和无空气情况下的热失活情况。结果证实，空气显著增强了湿热对该嗜热脂肪芽孢杆菌菌株的致死性。
