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电刺激系统治疗伤口愈合的可行性:巴巴多斯慢性溃疡患者的病例系列。

Feasibility of an electrostimulation system treatment for wound healing: a case series of patients with chronic ulcers in Barbados.

机构信息

Faculty of Medical Sciences, The University of the West Indies, Cave Hill, Barbados, West Indies.

Chronic Disease Research Centre, Tropical Medicine Research Institute, The University of the West Indies, Cave Hill, Barbados, West Indies.

出版信息

Int Wound J. 2016 Dec;13(6):1180-1189. doi: 10.1111/iwj.12438. Epub 2015 Mar 10.

Abstract

Major advances have been made in the development of new therapies for chronic wounds. Fenzian™, an electrostimulation system (ES), has been clinically used for a variety of conditions. The ES was recently tested in the Barbadian population for tolerability and acceptability by asthma patients, with encouraging results. Barbados has an estimated 170 people with diabetes having some form of lower-extremity amputation annually. Here, we describe a case series of 21 chronic ulcer patients with diabetes recruited as inpatients (n = 10) and outpatients (n = 11) in a pilot study to evaluate the feasibility and acceptability of ES in the Barbadian population. Results showed statistically significant improvement among those in the inpatient- versus outpatient-recruited group for wound perimeter (P = 0·04), wound surface area (P = 0·03) and wound volume (P = 0·08). We also demonstrate that the improvement continued after cessation of ES treatment. Participants reported increased levels of pain at the end of treatment, and there was no statistically significant change in the reported quality of life. Our results showed greater improvements in reduction of ulcer size for participants from the inpatient- versus outpatient-recruited group.

摘要

在开发慢性伤口新疗法方面取得了重大进展。Fenzian™ 是一种电刺激系统 (ES),已在各种情况下临床使用。最近,该 ES 在巴巴多斯的哮喘患者中进行了耐受性和可接受性测试,结果令人鼓舞。巴巴多斯每年约有 170 名糖尿病患者因某种形式的下肢截肢。在这里,我们描述了一项针对 21 名患有糖尿病的慢性溃疡患者的病例系列研究,这些患者作为住院患者(n = 10)和门诊患者(n = 11)在一项试点研究中招募,以评估 ES 在巴巴多斯人群中的可行性和可接受性。结果显示,在住院患者与门诊患者招募组中,伤口周长(P = 0·04)、伤口表面积(P = 0·03)和伤口体积(P = 0·08)均有统计学意义的改善。我们还证明,在停止 ES 治疗后,这种改善仍在继续。参与者在治疗结束时报告疼痛水平升高,生活质量报告没有统计学上的显著变化。我们的结果表明,住院患者与门诊患者招募组中,溃疡大小的减少幅度更大。

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本文引用的文献

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Electrical Stimulation Technologies for Wound Healing.用于伤口愈合的电刺激技术
Adv Wound Care (New Rochelle). 2014 Feb 1;3(2):81-90. doi: 10.1089/wound.2013.0459.

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