Kameda Kazuaki, Shirano Michinori, Hadano Yoshiro, Kasamatsu Yu, Nakamura Tadahiro, Ota Makiko, Goto Tetsushi
Department of Infectious Diseases, Osaka City General Hospital, Japan.
Intern Med. 2015;54(5):513-8. doi: 10.2169/internalmedicine.54.2438. Epub 2015 Jan 15.
Polyradiculopathy (PRP) is a rare but serious neurologic complication of cytomegalovirus (CMV) in patients with acquired immunodeficiency syndrome (AIDS). We herein report three cases of CMV PRP in patients with AIDS. Although providing a prompt diagnosis and initiating anti-CMV therapy may achieve clinical improvements, administering single-drug treatment may result in virologic failure. Therefore, introducing antiretroviral therapy is a key step for improving the treatment outcomes of CMV PRP.
多神经根病（PRP）是获得性免疫缺陷综合征（AIDS）患者中巨细胞病毒（CMV）罕见但严重的神经并发症。我们在此报告3例AIDS患者的CMV PRP病例。尽管及时诊断并开始抗CMV治疗可能会取得临床改善，但单一药物治疗可能会导致病毒学失败。因此，引入抗逆转录病毒疗法是改善CMV PRP治疗效果的关键步骤。
