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[疑似IgE介导疾病患者中对牛奶和鸡蛋致敏的患病率]

[Prevalence of sensitization to cow's milk and egg among patients with suspicion of IgE mediated diseases].

作者信息

Mopan José, Sánchez Jorge, Chinchilla Carlos, Cardona Ricardo

机构信息

Grupo de Alergología Clínica y Experimental, Universidad de Antioquia, Medellín, Colombia.

出版信息

Rev Alerg Mex. 2015 Jan-Mar;62(1):41-7.

PMID:25758112
Abstract

BACKGROUND

In Latin America, there are very few epidemiological data on food allergy and sensitization to milk and egg.

OBJECTIVE

To describe the frequency of sensitization to milk and egg in a population with suspicion of IgE mediated diseases.

MATERIAL AND METHOD

A retrospective and descriptive study was made with patients who consulted to our service of Allergy, with suspicion of exacerbation of possible IgE mediated diseases when eat certain foods. All patients had skin prick test including the suspected foods and milk and egg. Each patient had a complete clinical history.

RESULTS

Sensitization to at less one food was present in 29.7% of patients. Egg sensitization occurred in 6.1% of patients and it was associated with asthma, rhinitis and gastrointestinal eosinophilia in children younger than five years. Milk sensitization was present in 4.5% and was not associated with any disease.

CONCLUSIONS

In Colombia, sensitization to milk and egg is relatively low compared to that reported in other studies with population with high risk of sensitization. Because of the association between sensitization of egg and the risk of having respiratory symptoms and gastrointestinal eosinophilia, an egg sensitization could be and early marker of poor prognosis in atopic patients.

摘要

背景

在拉丁美洲,关于食物过敏以及对牛奶和鸡蛋致敏的流行病学数据非常少。

目的

描述疑似IgE介导疾病人群中对牛奶和鸡蛋致敏的频率。

材料与方法

对因食用某些食物疑似IgE介导疾病加重而前来我们过敏科就诊的患者进行了一项回顾性描述性研究。所有患者均进行了包括疑似食物、牛奶和鸡蛋在内的皮肤点刺试验。每位患者都有完整的临床病史。

结果

29.7%的患者对至少一种食物致敏。6.1%的患者对鸡蛋致敏,且与5岁以下儿童的哮喘、鼻炎和胃肠道嗜酸性粒细胞增多有关。4.5%的患者对牛奶致敏,且与任何疾病均无关联。

结论

在哥伦比亚,与其他针对高致敏风险人群的研究报告相比,对牛奶和鸡蛋的致敏率相对较低。由于对鸡蛋致敏与出现呼吸道症状和胃肠道嗜酸性粒细胞增多的风险之间存在关联,对鸡蛋致敏可能是特应性患者预后不良的早期指标。

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Rev Alerg Mex. 2015 Jan-Mar;62(1):41-7.
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