与原发性胆汁性肝硬化、干燥综合征及桥本甲状腺炎相关的显微镜下多血管炎。
Microscopic polyangiitis associated with primary biliary cirrhosis, Sjogren's syndrome and Hashimoto's thyroiditis.
作者信息
Ghorbel I Ben, Belfeki Nabil, Salem T Ben, Hamzaoui A, Khanfir M, Lamloum M, Miled M, Houman M H
机构信息
Department of Internal Medicine, La Rabta Hospital, Tunis, Tunisia.
出版信息
Saudi J Kidney Dis Transpl. 2015 Mar;26(2):359-62. doi: 10.4103/1319-2442.152515.
The association between microscopic polyangiitis (MPA) and primary biliary cirrhosis (PBC) has seldom been reported. We describe here a patient who presented with sensorimotor neuropathy along with hypothyroidism, renal failure and liver dysfunction. Detection of antinuclear antibodies at a titer of 1/800, anti-SSA, anti-SSB, anti-GP210, anti-microsomial and p-ANCA anti-myeloperoxydase antibodies along with renal, salivary and liver biopsy led to a diagnosis of MPA associated with PBC, Sjogren's syndrome and Hashimoto's thyroiditis.
显微镜下多血管炎（MPA）与原发性胆汁性肝硬化（PBC）之间的关联鲜有报道。我们在此描述一名患者，其出现感觉运动性神经病变，同时伴有甲状腺功能减退、肾衰竭和肝功能障碍。抗核抗体滴度为1/800、抗SSA、抗SSB、抗GP210、抗微粒体抗体和p-ANCA抗髓过氧化物酶抗体的检测，以及肾脏、唾液腺和肝脏活检，最终诊断为与PBC、干燥综合征和桥本甲状腺炎相关的MPA。
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