Serezhin B S
Arkh Patol. 1989;51(11):66-70.
The structures of a well-differentiated apudoma were combined with the foci of colloid carcinoma in a mammary gland tumour described. Two types of cells with argyrophil grains are distinguished depending on the argyrophil grain size, localization in the tumour cell cytoplasm and the ability to react with hormonal antisera. The first type cells correspond to the true apudocytes and produce serotonin and beta-endorphine. The smallest silver granules imitate the endocrine granules in the cells of the second type. The peculiar feature of this observation is in its clinical manifestations typical for the carcinoid syndrome.
在所述的乳腺肿瘤中，高分化的嗜银细胞瘤结构与胶样癌灶相结合。根据嗜银颗粒大小、在肿瘤细胞胞质中的定位以及与激素抗血清反应的能力，可区分出两种含嗜银颗粒的细胞。第一类细胞对应于真正的嗜银细胞，可产生5-羟色胺和β-内啡肽。最小的银颗粒类似于第二类细胞中的内分泌颗粒。这一观察结果的独特之处在于其具有类癌综合征典型的临床表现。
