Khosravi Shahla, Ardebili Hasan Eftekhar, Larijani Bagher, Nedjat Saharnaz, Nikbakht Nasrabadi Alireza, Ardebili Mehrdad Eftekhar, Dabiran Soheila, Samizadeh Esmaeil
Department of Community Medicine, Faculty Member of Medicine, Tehran School of Nursing and Midwifery, Tehran University of Medical Sciences, Poorsina Avenue, Ghods Avenue, Enghelab St., Tehran, Iran.
Department of Health Promotion and Education, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Aging Clin Exp Res. 2015 Dec;27(6):813-20. doi: 10.1007/s40520-015-0341-4. Epub 2015 Mar 12.
Andropause is a middle-age condition in which men experience changes in their physical, spiritual and emotional health. The association between andropause and psychological symptoms such as depression are not very clear yet.
The objective of this study was therefore to determine the association between the 'Aging Males Symptoms Scale' (AMS) and depression.
A cross sectional study was conducted among 521 old men. To collect data, the AMS and the Patient Health Questionnaires 2 and 9 were used to screen depression, in addition to questions on background and fertility. Multiple linear regression analysis was used to assess the association between andropause symptoms and depression.
Based on our results and the AMS score, 51.5% of the study population had clinical symptoms of androgen disorder, 3.7% of which had severe symptoms. There was a strong correlation between the AMS score and depression. Depression, diabetes, cigarette smoking and spousal age retained their significant associations even after entering the relevant demographic, anthropometric, smoking and disease variables in the multivariable model. As a positive predictive factor, depression had the strongest association with AMS.
Based on our results, there is a direct association between andropause symptoms and depression, where the increasing AMS score corresponds with the severity of depression.
Our results show the need of screening for depression when evaluating andropause symptoms.
男性更年期是一种中年时期的状况，男性在这一时期会经历身体、精神和情感健康方面的变化。男性更年期与诸如抑郁症等心理症状之间的关联尚不完全明确。
因此，本研究的目的是确定“老年男性症状量表”（AMS）与抑郁症之间的关联。
对521名老年男性进行了一项横断面研究。为收集数据，除了关于背景和生育能力的问题外，还使用AMS以及患者健康问卷2和9来筛查抑郁症。采用多元线性回归分析来评估男性更年期症状与抑郁症之间的关联。
根据我们的研究结果和AMS评分，51.5%的研究人群有雄激素紊乱的临床症状，其中3.7%有严重症状。AMS评分与抑郁症之间存在很强的相关性。即使在多变量模型中纳入了相关的人口统计学、人体测量学、吸烟和疾病变量后，抑郁症、糖尿病、吸烟和配偶年龄仍保持其显著关联。作为一个阳性预测因子，抑郁症与AMS的关联最为强烈。
根据我们的研究结果，男性更年期症状与抑郁症之间存在直接关联，AMS评分越高，抑郁症的严重程度越高。
我们的研究结果表明，在评估男性更年期症状时需要筛查抑郁症。
