Sawant Laxmichaya D, Venkat Shirin
Department of Obstetrics and Gynecology, Grant Medical Foundation, Ruby Hall Clinic, Pune, Maharashtra 411001, India.
Int J Reprod Med. 2013;2013:671954. doi: 10.1155/2013/671954. Epub 2013 Dec 29.
Fetal growth restriction or intrauterine growth restriction is one of the leading causes of perinatal mortality and morbidity in newborns. Fetal growth restriction is a complex multifactorial condition resulting from several fetal and maternal disorders. The objective of this study was twofold: first to examine the correlation between maternal parameters such as body mass index (BMI), nutritional status, anemia, and placental weight and diameter, and their effects on fetal growth and then to evaluate the effect of early screening by ultrasonography (USG) on the outcome of growth restricted pregnancies. In this study, 53 cases of fetal growth restriction were compared to 53 normal fetuses delivered in consecutive sequence. Growth restricted fetuses were delivered earlier in gestation, when compared with normal growth fetuses. Maternal anemia and malnutrition have significant association with the fetal growth restriction. Maternal anthropometry, such as low BMI, had effects on placental diameter and weight, which, in turn, adversely affected fetal weight. Thus, early USG screening along with robust screening for maternal BMI, nutritional status, and anemia can assist the obstetric team in providing early diagnosis, prompt intervention, and better outcome in pregnancy with fetal growth restriction.
胎儿生长受限或宫内生长受限是新生儿围产期死亡率和发病率的主要原因之一。胎儿生长受限是一种由多种胎儿和母体疾病导致的复杂多因素病症。本研究的目的有两个:一是检查母体参数如体重指数(BMI)、营养状况、贫血以及胎盘重量和直径之间的相关性,及其对胎儿生长的影响;二是评估超声检查(USG)早期筛查对生长受限妊娠结局的影响。在本研究中,将53例胎儿生长受限病例与连续分娩的53例正常胎儿进行了比较。与正常生长的胎儿相比,生长受限的胎儿在妊娠早期分娩。母体贫血和营养不良与胎儿生长受限有显著关联。母体人体测量指标,如低BMI,对胎盘直径和重量有影响,进而对胎儿体重产生不利影响。因此,早期超声检查筛查以及对母体BMI、营养状况和贫血进行全面筛查,有助于产科团队对胎儿生长受限的妊娠进行早期诊断、及时干预并获得更好的结局。