Araya Takao, von Wirén Nicolaus, Takahashi Hideki
a Department of Biochemistry and Molecular Biology; Michigan State University; East Lansing, MI USA.
Plant Signal Behav. 2014;9(7):e29302. doi: 10.4161/psb.29302.
CLE (CLAVATA3/embryo surrounding region (ESR)) peptides control meristem functions in plants. Our recent study highlights the critical role of a peptide-receptor signaling module composed of nitrogen (N)-responsive CLE peptides and the CLAVATA1 (CLV1) leucine-rich repeat receptor-like kinase in controlling lateral root development in Arabidopsis thaliana. CLE1, -3, -4 and -7 are expressed in root pericycle cells in Arabidopsis roots under N-limited growth conditions. Overexpression of these CLE genes inhibits lateral root emergence from the primary root. The inhibitory action of N-responsive CLE peptides on lateral root development requires the function of CLV1 expressed in phloem companion cells in roots, suggesting that downstream signals are transferred through phloem for systemic regulation of root system architecture. An additional mechanism downstream of CLV1 feedback-regulates transcript levels of N-responsive CLE genes in roots for fine-tuning the signal amplitude.
CLV3/胚周围区域（ESR）肽控制植物中的分生组织功能。我们最近的研究强调了由氮（N）响应性CLV3/ESR肽和富含亮氨酸重复序列的类受体激酶CLV1组成的肽-受体信号模块在控制拟南芥侧根发育中的关键作用。在氮限制生长条件下，CLV1、CLV3、CLV4和CLV7在拟南芥根的中柱鞘细胞中表达。这些CLV基因的过表达抑制了主根上侧根的出现。氮响应性CLV3/ESR肽对侧根发育的抑制作用需要根中韧皮部伴胞中表达的CLV1的功能，这表明下游信号通过韧皮部传递以对根系结构进行系统调节。CLV1下游的另一种机制反馈调节根中氮响应性CLV基因的转录水平，以微调信号幅度。
