From the Sections of Thoracic Imaging (I.M., C.T.L., M.A.B., A.H.E., J.T.A., R.D.R.) and Cardiovascular Imaging (M.A.B.), Imaging Institute, Section of Biomedical Engineering (J.H.K., N.M.), and Section of Thoracic and Cardiovascular Surgery, Heart and Vascular Institute (N.M.), Cleveland Clinic, 9500 Euclid Ave, Room L10, Cleveland, OH 44195.
Radiographics. 2015 Mar-Apr;35(2):327-56. doi: 10.1148/rg.352140149.
Heart failure is recognized with increasing frequency worldwide and often progresses to an advanced refractory state. Although the reference standard for treatment of advanced heart failure remains cardiac transplantation, the increasing shortage of donor organs and the unsuitability of many patients for transplantation surgery has led to a search for alternative therapies. One such therapy is mechanical circulatory support, which helps relieve the load on the ventricle and thereby allows it to recover function. In addition, there is increasing evidence supporting the use of mechanical devices as a bridge to recovery in patients with acute refractory heart failure. In this article, the imaging evaluation of various commonly used short- and long-term cardiac assist devices is discussed, and their relevant mechanisms of action and physiology are described. Imaging, particularly computed tomography (CT), plays a crucial role in preoperative evaluation for assessment of candidacy for implantation of a left ventricular assist device (LVAD) or total artificial heart (TAH). Also, echocardiography and CT are indispensable in assessment of complications associated with cardiac devices. Complications commonly associated with short-term assist devices include bleeding and malpositioning, whereas long-term devices such as LVADs may be associated with infection, pump thrombosis, and cannula malfunction, as well as bleeding. CT is also commonly performed for preoperative planning before LVAD or TAH explantation, replacement of a device or one of its components, and cardiac transplantation. Online supplemental material is available for this article.
心力衰竭在全球范围内的发病率越来越高,并且常常进展为晚期难治性状态。尽管心脏移植仍然是治疗晚期心力衰竭的参考标准,但供体器官的日益短缺和许多患者不适合移植手术,这促使人们寻求替代疗法。机械循环支持就是其中一种疗法,它有助于减轻心室的负荷,从而使其恢复功能。此外,越来越多的证据支持在急性难治性心力衰竭患者中使用机械装置作为恢复的桥梁。本文讨论了各种常用的短期和长期心脏辅助装置的影像学评估,并描述了它们的相关作用机制和生理学。影像学,特别是计算机断层扫描(CT),在评估左心室辅助装置(LVAD)或全人工心脏(TAH)植入的候选资格方面发挥着关键作用。此外,超声心动图和 CT 在评估与心脏装置相关的并发症方面也是不可或缺的。短期辅助装置常见的并发症包括出血和错位,而 LVAD 等长期装置可能与感染、泵血栓形成和导管功能障碍以及出血有关。在 LVAD 或 TAH 取出、装置或其部件更换以及心脏移植之前,通常也会进行 CT 以进行术前规划。本文提供了在线补充材料。