Buxadera-Palomero Judit, Canal Cristina, Torrent-Camarero Sergi, Garrido Beatriz, Javier Gil Francisco, Rodríguez Daniel
Biomaterials, Biomechanics and Tissue Engineering Group, E. U. d'Enginyeria Tècnica Industrial de Barcelona, Technical University of Catalonia (UPC), C/ Comte d'Urgell 187, 08036 Barcelona, Spain; CIBER de Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Maria de Luna 11, Ed. CEEI, 50118 Zaragoza, Spain; and Centre for Research in NanoEngineering (CRNE)-UPC, C/Pascual i Vila 15, 08028 Barcelona, Spain.
Biomaterials, Biomechanics and Tissue Engineering Group, Department of Materials Science and Metallurgy, E. T. S. d'Enginyeria Industrial de Barcelona, Technical University of Catalonia (UPC), Av. Diagonal 647, 08028 Barcelona, Spain; CIBER de Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Maria de Luna 11, Ed. CEEI, 50118 Zaragoza, Spain; and Centre for Research in NanoEngineering (CRNE)-UPC, C/Pascual i Vila 15, 08028 Barcelona, Spain.
Biointerphases. 2015 Jun 12;10(2):029505. doi: 10.1116/1.4913376.
Titanium dental implants are commonly used for the replacement of lost teeth, but they present a considerable number of failures due to the infection on surrounding tissues. The aim of this paper is the development of a polyethylene glycol-like (PEG-like) coating on the titanium surface by plasma polymerization to obtain a novel improved surface with suitable low bacterial adhesion and adequate cell response. Surface analysis data of these coatings are presented, in particular, water contact angle, surface roughness, and film chemistry, demonstrating the presence of a PEG-like coating. Streptococcus sanguinis and Lactobacillus salivarius bacterial adhesion assays showed a decreased adhesion on the plasma polymerized samples, while cell adhesion of fibroblasts and osteoblasts on the treated surfaces was similar to control surfaces. Thus, the PEG-like antifouling coating obtained by plasma polymerization on Ti confers this biomaterial's highly suitable properties for dental applications, as they reduce the possibility of infection while allowing the tissue integration around the implant.
钛牙种植体常用于替代缺失的牙齿，但由于周围组织感染，它们存在相当数量的失败案例。本文的目的是通过等离子体聚合在钛表面开发一种聚乙二醇类（PEG类）涂层，以获得具有合适的低细菌粘附性和充分细胞反应的新型改良表面。本文展示了这些涂层的表面分析数据，特别是水接触角、表面粗糙度和薄膜化学性质，证明了PEG类涂层的存在。血链球菌和唾液乳杆菌的细菌粘附试验表明，等离子体聚合样品上的粘附减少，而成纤维细胞和成骨细胞在处理过的表面上的细胞粘附与对照表面相似。因此，通过等离子体聚合在钛上获得的PEG类防污涂层赋予了这种生物材料在牙科应用中非常合适的性能，因为它们降低了感染的可能性，同时允许植入物周围的组织整合。
