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全膝关节置换翻修术病因学的最新进展——1449例回顾性调查中的明显趋势

Update on the etiology of revision TKA -- Evident trends in a retrospective survey of 1449 cases.

作者信息

Calliess Tilman, Ettinger Max, Hülsmann Natalie, Ostermeier Sven, Windhagen Henning

机构信息

Department of Orthopaedic Surgery, Hannover Medical School, Anna-von-Borries-Str. 3, 30625 Hannover, Germany.

Orthopädische Praxis und Gelenk-Klinik, Alte Bundesstrasse 58, 79194 Gundelfingen, Germany.

出版信息

Knee. 2015 Jun;22(3):174-9. doi: 10.1016/j.knee.2015.02.007. Epub 2015 Mar 11.

Abstract

BACKGROUND

A working and complete knowledge of the different causes of dysfunction and pain after TKA is essential for the ability to correctly determine the cause of failure and to address this problem specifically. The purpose of this study was to update the etiology of implant failure. New diagnosis and current trends should be displayed.

METHODS

All TKA revisions performed in our institution between 2001 and 2010 were reviewed retrospectively. Patient demographics and the precise indication for the surgery were documented. Descriptive statistical analyses and association analyses of both the diagnosis and patient demographics were performed.

RESULTS

Within our collective of 1449 revision TKA a total of 40 different pathologies leading to revision surgery were identified and categorized. Overall 68.5% of the revisions were categorized aseptic, 31.5% as septic implant failure. Some recently debated diagnoses like low-grade-infection showed a high increase in incidence whereas classic failure mechanisms like polyethylene wear showed a decrease over the time.

CONCLUSION

We believe that this study successfully updates the current knowledge of different failure mechanisms in revision TKA, which have to be considered on dysfunction or pain after surgery. We were able to evaluate the clinical relevance of each pathology and could shift from implant related problems like wear to more surgical problems like instability and or malalignment over the last years. With a higher alertness to chronic low-grade-infections the incidence of infection is even increasing.

LEVEL OF EVIDENCE

Level II, economic and decision analysis.

摘要

背景

全面了解全膝关节置换术(TKA)后功能障碍和疼痛的不同原因,对于正确确定失败原因并针对性解决问题至关重要。本研究旨在更新植入物失败的病因,展示新的诊断方法和当前趋势。

方法

回顾性分析2001年至2010年间在我院进行的所有TKA翻修手术。记录患者人口统计学资料和手术的确切指征。对诊断和患者人口统计学资料进行描述性统计分析和关联分析。

结果

在我们的1449例TKA翻修病例中,共确定并分类了40种导致翻修手术的不同病理情况。总体而言,68.5%的翻修病例归类为无菌性,31.5%为感染性植入物失败。一些最近有争议的诊断,如低度感染,发病率大幅上升,而像聚乙烯磨损这样的经典失败机制则随时间下降。

结论

我们认为本研究成功更新了TKA翻修中不同失败机制的现有知识,这些知识在术后功能障碍或疼痛时必须予以考虑。我们能够评估每种病理情况的临床相关性,并且在过去几年中,关注点已从磨损等与植入物相关的问题转向不稳定和/或对线不良等更多手术问题。随着对慢性低度感染的警惕性提高,感染发病率甚至还在上升。

证据水平

二级,经济和决策分析。

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