Evans L H, Cloyd M W
Proc Natl Acad Sci U S A. 1985 Jan;82(2):459-63. doi: 10.1073/pnas.82.2.459.
A group of mink cell focus-forming (MCF) viruses was derived by inoculation of NFS/N mice with Moloney murine leukemia virus (Mo-MuLV 1387) and was compared to a similarly derived group of MCF viruses from mice inoculated with Friend MuLV (Fr-MuLV 57). Antigenic analyses using monoclonal antibodies specific for MCF virus and xenotropic MuLV envelope proteins and genomic structural analyses by RNase T1-resistant oligonucleotide finger-printing indicated that the Moloney and Friend MCF viruses arose by recombination of the respective ecotropic MuLVs with different endogenous retrovirus sequences of NFS mice.
通过用莫洛尼鼠白血病病毒(Mo-MuLV 1387)接种NFS/N小鼠获得了一组貂细胞集落形成(MCF)病毒,并将其与通过接种弗氏鼠白血病病毒(Fr-MuLV 57)的小鼠以类似方式获得的一组MCF病毒进行了比较。使用针对MCF病毒和嗜异性MuLV包膜蛋白的单克隆抗体进行的抗原分析,以及通过耐核糖核酸酶T1寡核苷酸指纹图谱进行的基因组结构分析表明,莫洛尼和弗氏MCF病毒是由各自的亲嗜性MuLV与NFS小鼠不同的内源性逆转录病毒序列重组产生的。