Ru Wenwen, Wang Dongliang, Xu Yunpeng, He Xianxian, Sun Yang-En, Qian Liyan, Zhou Xiangshan, Qin Yufeng
National Engineering Technology Research Center of Glue of Traditional Medicine, 2. Shandong Dong-E-E-Jiao Co., Ltd., Dong'e, Shandong, China.
Drug Discov Ther. 2015 Feb;9(1):23-32. doi: 10.5582/ddt.2015.01004.
Ginseng, Panax ginseng (C. A. Mey.), is a well-known Chinese traditional medicine in the Far East and has gained popularity in the West during the last decade. There is extensive literature on the chemical constituents and bioactivities of ginseng. In this paper we compiled the chemical constituents isolated and detected from ginseng including polysaccharides, ginsenosides, peptides, polyacetylenic alcohols, fatty acids, etc. Meanwhile we summarized the biological activities of ginseng, which have been reported over the past few decades, including: anti-aging activity, anti-diabetic activity, immunoregulatory activity, anti-cancer activity, neuroregulation activity, wound and ulcer healing activity, etc. Nevertheless, further studies to exploit other kinds of constituents and new biological activities of ginseng are still necessary to facilitate research and development in the future.
人参,五加科人参属植物(C. A. Mey.),是远东地区著名的中国传统药物,在过去十年中在西方也颇受欢迎。关于人参的化学成分和生物活性有大量文献。在本文中,我们汇编了从人参中分离和检测到的化学成分,包括多糖、人参皂苷、肽、聚乙炔醇、脂肪酸等。同时,我们总结了过去几十年来报道的人参的生物活性,包括:抗衰老活性、抗糖尿病活性、免疫调节活性、抗癌活性、神经调节活性、伤口和溃疡愈合活性等。然而,为了促进未来的研究和开发,仍有必要进一步研究以开发人参的其他种类成分和新的生物活性。