Aydogmus S, Kelekci S, Aydogmus H, Demir M, Yilmaz B, Sutcu R
Department of Gynaecology and Obstetrics, İzmir Katip Çelebi University School of Medicine, İzmir, Turkey,
Int Urogynecol J. 2015 Aug;26(8):1179-84. doi: 10.1007/s00192-015-2671-3. Epub 2015 Mar 20.
Vitamin D affects skeletal muscle strength and functions via various mechanisms. Strength and/or functional dysfunctions of the pelvic floor muscles may be associated with the distortion of pelvic floor functions. We hypothesized that vitamin D deficiency may contribute to pelvic floor dysfunction (PFD) by affecting pelvic floor muscle strength (PFMS). The aim of this study was to assess the effect of vitamin D deficiency during pregnancy on postpartum PFMS.
This cross-sectional study was conducted in a university hospital. One hundred and eighty pregnant women were admitted to our hospital in their third trimester and compared with 156 healthy nulliparous women. Venous blood samples for examining vitamin D levels were taken from each participant and stored at -80 °C. At 8-10 weeks postpartum, patients were invited to the hospital, asked about their PFD symptoms, and PFMS was measured using a perineometer.
There was no statistical significance among groups regarding mean age, maternal age, and weight at delivery. Postpartum PFMS and duration in vitamin D-deficient women were significantly lower than those without the deficiency. Vitamin D-deficient vaginal delivery cases (group I) had a postpartum PFMS average of 21.96 ± 7.91 cm-H₂O, nonvitamin D-deficient normal delivery cases (group III) had a PFMS of 29.66 ± 10.3 cm-H₂O (p = 0.001). In the cesarean delivery groups, vitamin D-deficient (group II) and nonvitamin D-deficient (group IV) cases had PFMS values of 32.23 ± 9.66 and 35.53 ± 15.58 cm-H₂O respectively (p = 0.258).
Lower vitamin D levels in the third trimester correlates with decreased PFMS.
维生素D通过多种机制影响骨骼肌力量和功能。盆底肌肉的力量和/或功能障碍可能与盆底功能的扭曲有关。我们假设维生素D缺乏可能通过影响盆底肌肉力量（PFMS）导致盆底功能障碍（PFD）。本研究的目的是评估孕期维生素D缺乏对产后PFMS的影响。
本横断面研究在一家大学医院进行。180名孕妇在孕晚期入院，并与156名健康未生育女性进行比较。从每位参与者采集用于检测维生素D水平的静脉血样本，并储存在-80°C。产后8至10周，邀请患者到医院，询问她们的PFD症状，并使用会阴压力计测量PFMS。
各组在平均年龄、产妇年龄和分娩时体重方面无统计学意义。维生素D缺乏女性的产后PFMS和持续时间显著低于非缺乏女性。维生素D缺乏的阴道分娩病例（I组）产后PFMS平均为21.96±7.91cm-H₂O，非维生素D缺乏的正常分娩病例（III组）PFMS为29.66±10.3cm-H₂O（p=0.001）。在剖宫产组中，维生素D缺乏（II组）和非维生素D缺乏（IV组）病例的PFMS值分别为32.23±9.66和35.53±15.58cm-H₂O（p=0.258）。
孕晚期较低的维生素D水平与PFMS降低相关。
