创伤筛查问卷预测精神病患者创伤后应激障碍的有效性。
Predictive validity of the Trauma Screening Questionnaire in detecting post-traumatic stress disorder in patients with psychotic disorders.
机构信息
Paul A. J. M. de Bont, MSc, Community Mental Health Service GGZ Oost Brabant Land van Cuijk en Noord Limburg, Boxmeer and Radboud University Nijmegen, Behavioural Science Institute, NijCare, The Netherlands; David P. G. van den Berg, MSc, Parnassia Psychiatric Institute, Den Haag, The Netherlands; Berber M. van der Vleugel, MSc, Community Mental Health Service GGZ Noord-Holland Noord, Alkmaar, The Netherlands; Carlijn de Roos, MSc, MHO Rivierduinen, Leiden, The Netherlands; Ad de Jongh, PhD, Department of Behavioral Sciences, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and VU University Amsterdam, Amsterdam, The Netherlands and School of Health Sciences, Salford University, Manchester, UK; Mark van der Gaag, PhD, VU University Amsterdam and EMGO Institute for Health and Care Research, Department of Clinical Psychology, Amsterdam and Parnassia Psychiatric Institute, Den Haag, The Netherlands; Agnes van Minnen, PhD, Radboud University Nijmegen, Behavioural Science Institute, NijCare and MHO 'Pro Persona', Centre for Anxiety Disorders Netherlands, Nijmegen, The Netherlands.
出版信息
Br J Psychiatry. 2015 May;206(5):408-16. doi: 10.1192/bjp.bp.114.148486. Epub 2015 Mar 19.
BACKGROUND
Post-traumatic stress disorder (PTSD) is highly prevalent in patients with a psychotic disorder. Because a PTSD diagnosis is often missed in patients with psychosis in routine care, a valid screening instrument could be helpful.
AIMS
To determine the validity of the Trauma Screening Questionnaire (TSQ) as a screening tool for PTSD among individuals with psychotic disorders.
METHOD
Among 2608 patients with a psychotic disorder, the rate of trauma exposure was determined and the TSQ was administered to screen for PTSD. PTSD status was verified in 455 patients using the Clinician-Administered PTSD Scale (trial registration: ISRCTN 79584912).
RESULTS
Trauma exposure was reported by 78.2% of the 2608 patients. PTSD prevalence was estimated at 16% (95% CI 14.6-17.4%) compared with 0.5% reported in the patients' clinical charts. A TSQ cut-off score of six predicted PTSD with 78.8% sensitivity, 75.6% specificity, 44.5% correct positives and 93.6% correct negatives.
CONCLUSIONS
The TSQ seems to be a valid screening tool for PTSD in patients with a psychotic disorder.
背景
创伤后应激障碍（PTSD）在精神病患者中非常普遍。由于在常规护理中，精神病患者的 PTSD 诊断常常被忽视，因此有效的筛查工具可能会有所帮助。
目的
确定创伤筛查问卷（TSQ）作为精神病患者 PTSD 筛查工具的有效性。
方法
在 2608 名患有精神病的患者中，确定了创伤暴露率，并使用 TSQ 对 PTSD 进行了筛查。在 455 名患者中使用临床医生管理的 PTSD 量表（试验注册：ISRCTN79584912）验证了 PTSD 状态。
结果
2608 名患者中有 78.2%报告了创伤暴露。与患者临床记录中报告的 0.5%相比，PTSD 患病率估计为 16%（95%CI14.6-17.4%）。TSQ 截断分数为 6 预测 PTSD 的灵敏度为 78.8%，特异性为 75.6%，正确阳性率为 44.5%，正确阴性率为 93.6%。
结论
TSQ 似乎是精神病患者 PTSD 的有效筛查工具。
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