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航空工业装配工人的铬职业暴露

Occupational Exposure to Chromium of Assembly Workers in Aviation Industries.

作者信息

Genovese G, Castiglia L, Pieri M, Novi C, d'Angelo R, Sannolo N, Lamberti M, Miraglia N

机构信息

a Department of Experimental Medicine - Section of Hygiene, Occupational Medicine and Forensic Medicine - Occupational Medicine Area - Second University of Naples , Naples , Italy.

出版信息

J Occup Environ Hyg. 2015;12(8):518-24. doi: 10.1080/15459624.2015.1019075.

Abstract

Aircraft are constructed by modules that are covered by a "primer" layer, which can often contain hexavalent chromium [Cr(VI)], known carcinogen to humans. While the occupational exposure to Cr(VI) during aircraft painting is ascertained, the exposure assessment of assembly workers (assemblers) requires investigations. Three biological monitoring campaigns (BM-I,II,III) were performed in an aviation industry, on homogeneous groups of assemblers (N = 43) and controls (N = 23), by measuring chromium concentrations in end-shift urine collected at the end of the working week and the chromium concentration difference between end- and before-shift urines. BM-I was conducted on full-time workers, BM-II was performed on workers after a 3-4 day absence from work, BM-III on workers using ecoprimers with lower Cr(VI) content. Samples were analyzed by atomic absorption spectroscopy and mean values were compared by T-test. Even if Cr concentrations measured during BM-I were lower than Biological Exposure Indices by ACGIH, statistically significant differences were found between urinary Cr concentrations of workers and controls. Despite 3-4 days of absence from work, urinary chromium concentrations measured during BM-II were still higher than references from nonoccupationally exposed populations. In the BM-III campaign, the obtained preliminary results suggested the efficacy of using ecoprimers. The healthcare of workers exposed to carcinogenic agents follows the principle of limiting the exposure to "the minimum technically possible". The obtained results evidence that assemblers of aviation industries, whose task does not involve the direct use of primers containing Cr(VI), show an albeit slight occupational exposure to Cr(VI), that must be carefully taken into consideration in planning suitable prevention measures during risk assessment and management processes.

摘要

飞机由模块构建而成,这些模块覆盖有一层“底漆”,其中通常可能含有六价铬[Cr(VI)],这是一种已知的对人类致癌的物质。虽然飞机喷漆过程中六价铬的职业暴露情况已确定,但装配工人(组装工)的暴露评估仍需进行调查。在一家航空工业企业中,针对同质的组装工群体(N = 43)和对照组(N = 23)开展了三项生物监测活动(BM-I、II、III),通过测量工作周结束时采集的班末尿液中的铬浓度以及班末和班前尿液之间的铬浓度差值来进行。BM-I针对的是全职员工,BM-II针对的是缺勤3 - 4天之后的员工,BM-III针对的是使用六价铬含量较低的生态底漆的员工。样本通过原子吸收光谱法进行分析,平均值通过T检验进行比较。即使BM-I期间测得的铬浓度低于美国政府工业卫生学家会议(ACGIH)的生物暴露指数,但在工人和对照组的尿铬浓度之间仍发现了具有统计学意义的差异。尽管缺勤3 - 4天,但BM-II期间测得的尿铬浓度仍高于非职业暴露人群的参考值。在BM-III活动中,获得的初步结果表明使用生态底漆是有效的。接触致癌物质的工人的医疗保健遵循将暴露限制在“技术上可行的最低限度”这一原则。所获得的结果证明,航空工业的组装工,其任务并不涉及直接使用含六价铬的底漆,尽管对六价铬的职业暴露程度较轻,但在风险评估和管理过程中规划适当的预防措施时,必须仔细考虑这一点。

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