Fryczkowski A W, Peiffer R L, Merritt J C, Kraybill E N, Eifrig D E
Arch Ophthalmol. 1985 Feb;103(2):224-8. doi: 10.1001/archopht.1985.01050020076025.
Clinicoanatomopathologic correlations in a case of the retinopathy of prematurity are reported. A premature infant delivered at 28 weeks of gestation (weight, 900 g) was hospitalized for a number of health problems, including bronchopulmonary dysplasia and respiratory distress syndrome. Ophthalmic examination, at the age of 5 months, disclosed stage 1B retinopathy of prematurity. The patient died at the age of 161 days; both eyes were taken for scanning electron microscopy and histopathologic studies. Scanning electron microscopy findings included absence of retinal capillaries, anterior uveal neovascularization originating from the venous side, and a coincidental typical coloboma of the optic nerve and choriocapillaris. Histopathologic findings confirmed iris stromal neovascularization, showed retinal neovascularization with proliferation into the vitreous and avascular areas between the midperiphery and ora serrata.
报告了一例早产儿视网膜病变的临床解剖病理学相关性。一名妊娠28周出生的早产儿（体重900克）因多种健康问题住院，包括支气管肺发育不良和呼吸窘迫综合征。5个月大时的眼科检查发现1B期早产儿视网膜病变。该患者于161天时死亡；双眼被用于扫描电子显微镜和组织病理学研究。扫描电子显微镜检查结果包括视网膜毛细血管缺失、起源于静脉侧的前葡萄膜新生血管形成，以及视神经和脉络膜毛细血管的巧合性典型缺损。组织病理学检查结果证实虹膜基质新生血管形成，显示视网膜新生血管形成并增殖进入玻璃体以及中周部和锯齿缘之间的无血管区域。
