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固相结合肽:纳米生物技术的智能工具。

Solid-binding peptides: smart tools for nanobiotechnology.

机构信息

Department of Chemistry and Biomolecular Sciences, Macquarie University, Sydney, Australia.

Department of Chemistry and Biomolecular Sciences, Macquarie University, Sydney, Australia; Department of Molecular Medicine & Pathology, Medical School, University of Auckland, Auckland, New Zealand.

出版信息

Trends Biotechnol. 2015 May;33(5):259-68. doi: 10.1016/j.tibtech.2015.02.005. Epub 2015 Mar 19.

Abstract

Over the past decade, solid-binding peptides (SBPs) have been used increasingly as molecular building blocks in nanobiotechnology. These peptides show selectivity and bind with high affinity to the surfaces of a diverse range of solid materials including metals, metal oxides, metal compounds, magnetic materials, semiconductors, carbon materials, polymers, and minerals. They can direct the assembly and functionalisation of materials, and have the ability to mediate the synthesis and construction of nanoparticles and complex nanostructures. As the availability of newly synthesised nanomaterials expands rapidly, so too do the potential applications for SBPs.

摘要

在过去的十年中,固相结合肽 (SBPs) 越来越多地被用作纳米生物技术中的分子构建块。这些肽表现出选择性,并与各种固体材料的表面具有高亲和力结合,包括金属、金属氧化物、金属化合物、磁性材料、半导体、碳材料、聚合物和矿物质。它们可以指导材料的组装和功能化,并具有介导纳米粒子和复杂纳米结构的合成和构建的能力。随着新合成的纳米材料的可用性迅速扩大,SBPs 的潜在应用也在增加。

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