Kane Ravi S, Stroock Abraham D
Department of Chemical and Biological Engineering, Rensselaer Polytechnic Institute, Troy, New York 12180, USA.
Biotechnol Prog. 2007 Mar-Apr;23(2):316-9. doi: 10.1021/bp060388n. Epub 2007 Mar 3.
We review recent research that involves the interaction of nanomaterials such as nanoparticles, nanowires, and carbon nanotubes with proteins. We begin with a focus on the fundamentals of the structure and function of proteins on nanomaterials. We then review work in three areas that exploit these interactions: (1) sensing, (2) assembly of nanomaterials by proteins and proteins by nanomaterials, and (3) interactions with cells. We conclude with the identification of challenges and opportunities for the future.
我们回顾了近期涉及纳米颗粒、纳米线和碳纳米管等纳米材料与蛋白质相互作用的研究。我们首先关注蛋白质在纳米材料上的结构和功能基础。然后我们回顾了利用这些相互作用的三个领域的工作:(1)传感,(2)蛋白质对纳米材料的组装以及纳米材料对蛋白质的组装,(3)与细胞的相互作用。我们最后确定了未来的挑战和机遇。