Kijsamanmith Kanittha, Sasananda Panita, Ngamlertnapaporn Punnavit, Trairattanathada Suphalak, Kijsiripanth Atis
Department of Oral Biology, Faculty of Dentistry, Mahidol University, Bangkok, Thailand.
J Dent Sci. 2025 Apr;20(2):844-853. doi: 10.1016/j.jds.2024.09.023. Epub 2024 Oct 5.
BACKGROUND/PURPOSE: The stannous fluoride pretreatment of dentin may compromise the bond formation of the dentinal adhesive system. This study aimed to determine the effect of stannous fluoride (SnF) desensitizing toothpaste on immediate dentin sealing ability (IDS) of universal adhesive in human intact dentin using dentin permeability test and scanning electron microscopy (SEM) and energy dispersive x-ray spectroscopy (EDS).
Sixty sound dentin specimens were prepared from 60 extracted intact third molars, then treated with 17 % EDTA for 60 s to simulate hypersensitive dentin, and randomly divided into 2 series. Series 1 (dentin permeability test; n = 40) had 4 different treatment groups: (1) universal adhesive (self-etch mode), (2) universal adhesive (total-etch mode), (3) SnF pretreatment + universal adhesive (self-etch), (4) SnF pretreatment + universal adhesive (total-etch). The IDS of each group was the percentage decrease of hydraulic conductance of dentin after bonding. Series 2 (n = 20) was SEM-EDS analysis of different treated dentin before bonding. The data were analyzed using 2-way ANOVA and Tukey test.
In groups of no SnF pretreatment, the IDS of universal adhesive were 79.53 ± 20.71 and 77.34 ± 18.14 % for self-etch and total-etch mode, respectively. In groups of SnF pretreatment, the corresponding values were 71.54 ± 15.56 and 69.56 ± 9.92 %, respectively. Although SnF pretreated-dentin had the remarkable signals of silicon and tin, there were no significant reductions in the IDS of universal adhesive ( < 0.05).
SnF desensitizing toothpaste has no adverse effect on the immediate dentin sealing ability of universal adhesive.
背景/目的：牙本质的氟化亚锡预处理可能会损害牙本质黏结系统的黏结形成。本研究旨在通过牙本质渗透性测试、扫描电子显微镜（SEM）和能量色散X射线光谱仪（EDS），确定含氟化亚锡（SnF）的脱敏牙膏对人完整牙本质中通用黏合剂的即时牙本质封闭能力（IDS）的影响。
从60颗完整拔除的第三磨牙制备60个健康牙本质样本，然后用17%的乙二胺四乙酸（EDTA）处理60秒以模拟过敏牙本质，并随机分为2组。第1组（牙本质渗透性测试；n = 40）有4个不同的处理组：（1）通用黏合剂（自酸蚀模式），（2）通用黏合剂（全酸蚀模式），（3）氟化亚锡预处理+通用黏合剂（自酸蚀），（4）氟化亚锡预处理+通用黏合剂（全酸蚀）。每组的IDS是黏结后牙本质水力传导率降低的百分比。第2组（n = 20）是对不同处理的牙本质黏结前进行SEM-EDS分析。数据采用双向方差分析和Tukey检验进行分析。
在未进行氟化亚锡预处理的组中，通用黏合剂自酸蚀和全酸蚀模式的IDS分别为79.53±20.71%和77.34±18.14%。在进行氟化亚锡预处理的组中，相应的值分别为71.54±15.56%和69.56±9.92%。虽然经氟化亚锡预处理的牙本质有明显的硅和锡信号，但通用黏合剂的IDS没有显著降低（P<0.05）。
含氟化亚锡的脱敏牙膏对通用黏合剂的即时牙本质封闭能力没有不良影响。
