Zhang Qi-Hui, Tian Li, Sun Zong-Liang, Fang Shuai, Cai Gong-Li, Wang Yu-Jia, Pei Yue-Hu
a School of Chemistry and Chemical Engineering, Chongqing University , Chongqing 400044 , China.
J Asian Nat Prod Res. 2015 May;17(5):497-503. doi: 10.1080/10286020.2015.1009899. Epub 2015 Mar 23.
Two new secondary metabolites, (2S)-5-acetamidopentyl-2-hydroxypropanoate (1) and 2, 5, 7-trihydroxy-4-(3'-methylbut-2'-en-1'-yl) oxy-2H-naphtho [1, 8-b c] furan-9-one (2) were isolated from the marine-derived fungus Nigrospora sphaerica. The structures were established on the basis of their spectroscopic data, including 1D NMR and 2D NMR, HR-TOF-MS, and the absolute configuration of compound 1 was determined by the Mosher method.
从海洋来源的球形黑孢菌中分离出两种新的次生代谢产物，(2S)-5-乙酰氨基戊基-2-羟基丙酸酯(1)和2,5,7-三羟基-4-(3'-甲基丁-2'-烯-1'-基)氧基-2H-萘并[1,8-bc]呋喃-9-酮(2)。根据它们的光谱数据（包括一维核磁共振和二维核磁共振、高分辨飞行时间质谱）确定了其结构，化合物1的绝对构型通过莫舍尔方法确定。
