Bhattarai S, Agrawal S, Rijal A
Nepal Med Coll J. 2014 Sep;16(1):37-41.
Hand eczema (HE) is a common and distressing condition that is perplexing to the patient and the physician alike. To study the frequency and clinical features of hand eczema and to correlate the frequency of atopy and contact sensitization with different clinical features a total of 61 clinically diagnosed patient of Hand eczema were included within a period of one year. Patch test was done in 47 patients and graded accordingly. The frequency of hand eczema was 0.57%. Morphologically pompholyx was the most common type while aetiologically endogenous hand eczema was the commonest. Contact allergy was observed in 55.3% of the cases of which nickel sulphate (18.5%) was found to be the commonest sensitiser followed by Gentamicin and Fragrance mix though contact allergens with positive patch test in different morphological types of hand eczema have no apparent relevance but it still could contribute to the persistence or exacerbation of hand eczema.
手部湿疹(HE)是一种常见且令人苦恼的病症,患者和医生对此都感到困惑。为了研究手部湿疹的发病率和临床特征,并将特应性和接触致敏的发生率与不同的临床特征相关联,在一年的时间里共纳入了61例临床诊断为手部湿疹的患者。对47例患者进行了斑贴试验并据此分级。手部湿疹的发病率为0.57%。形态学上,汗疱疹是最常见的类型,而病因学上内源性手部湿疹最为常见。在55.3%的病例中观察到接触性过敏,其中硫酸镍(18.5%)被发现是最常见的致敏原,其次是庆大霉素和香料混合物。尽管不同形态类型的手部湿疹中斑贴试验阳性的接触性变应原并无明显相关性,但它仍可能导致手部湿疹的持续或加重。