A new chance to beat diabetic kidney disease: innate immunity and MCP-1: a matter of good and bad macrophages?

作者信息

Gnudi Luigi

机构信息

Unit for Metabolic Medicine Cardiovascular Division, Department of Diabetes and Endocrinology, School of Life Science and Medicine, King's College, London, UK.

出版信息

Nephrol Dial Transplant. 2015 Apr;30(4):525-7. doi: 10.1093/ndt/gfv053.

DOI:10.1093/ndt/gfv053

PMID:25801635

Abstract

摘要

相似文献

A new chance to beat diabetic kidney disease: innate immunity and MCP-1: a matter of good and bad macrophages?

Nephrol Dial Transplant. 2015 Apr;30(4):525-7. doi: 10.1093/ndt/gfv053.

Systemic Monocyte Chemotactic Protein-1 Inhibition Modifies Renal Macrophages and Restores Glomerular Endothelial Glycocalyx and Barrier Function in Diabetic Nephropathy.全身性单核细胞趋化蛋白-1抑制可改变糖尿病肾病中的肾巨噬细胞，并恢复肾小球内皮糖萼和屏障功能。

Am J Pathol. 2017 Nov;187(11):2430-2440. doi: 10.1016/j.ajpath.2017.07.020. Epub 2017 Aug 22.

Monocyte chemoattractant protein-1 promotes the development of diabetic renal injury in streptozotocin-treated mice.单核细胞趋化蛋白-1促进链脲佐菌素诱导的糖尿病小鼠肾损伤的发展。

Kidney Int. 2006 Jan;69(1):73-80. doi: 10.1038/sj.ki.5000014.

MCP-1/CCL2: a new diagnostic marker and therapeutic target for progressive renal injury in diabetic nephropathy.单核细胞趋化蛋白-1/CCL2：糖尿病肾病进展性肾损伤的新型诊断标志物及治疗靶点

Am J Physiol Renal Physiol. 2008 Apr;294(4):F697-701. doi: 10.1152/ajprenal.00016.2008. Epub 2008 Feb 13.

Rosiglitazone protects diabetic rats against kidney disease through the suppression of renal moncyte chemoattractant protein-1 expression.罗格列酮通过抑制肾单核细胞趋化蛋白-1的表达来保护糖尿病大鼠免受肾脏疾病的侵害。

J Diabetes Complications. 2009 Mar-Apr;23(2):124-9. doi: 10.1016/j.jdiacomp.2007.11.012. Epub 2008 Apr 16.

Leishmania-derived murine monocyte chemoattractant protein 1 enhances the recruitment of a restrictive population of CC chemokine receptor 2-positive macrophages.利什曼原虫衍生的小鼠单核细胞趋化蛋白1增强了CC趋化因子受体2阳性巨噬细胞的限制性群体的募集。

Infect Immun. 2007 Feb;75(2):653-65. doi: 10.1128/IAI.01314-06. Epub 2006 Nov 6.

Effect of retinoic acid in experimental diabetic nephropathy.维甲酸在实验性糖尿病肾病中的作用。

Immunol Cell Biol. 2004 Dec;82(6):568-76. doi: 10.1111/j.1440-1711.2004.01287.x.

Monocyte chemoattractant protein-1/CC chemokine ligand 2 controls microtubule-driven biogenesis and leukotriene B4-synthesizing function of macrophage lipid bodies elicited by innate immune response.单核细胞趋化蛋白-1/CC趋化因子配体2控制由先天免疫反应引发的巨噬细胞脂质体的微管驱动生物合成和白三烯B4合成功能。

J Immunol. 2007 Dec 15;179(12):8500-8. doi: 10.4049/jimmunol.179.12.8500.

Simultaneous activation of innate and adaptive immunity participates in the development of renal injury in a model of heavy proteinuria.在一种重度蛋白尿模型中，固有免疫和适应性免疫的同时激活参与了肾损伤的发展。

Biosci Rep. 2018 Jul 12;38(4). doi: 10.1042/BSR20180762. Print 2018 Aug 31.

Mesenchymal stem cells transplantation ameliorates glomerular injury in streptozotocin-induced diabetic nephropathy in rats via inhibiting macrophage infiltration.间质干细胞移植通过抑制巨噬细胞浸润改善链脲佐菌素诱导的糖尿病肾病大鼠的肾小球损伤。

Int Immunopharmacol. 2013 Oct;17(2):275-82. doi: 10.1016/j.intimp.2013.05.031. Epub 2013 Jun 19.

引用本文的文献

Coreopsis tinctoria Nutt ameliorates high glucose-induced renal fibrosis and inflammation via the TGF-β1/SMADS/AMPK/NF-κB pathways.金鸡菊通过 TGF-β1/SMADS/AMPK/NF-κB 通路改善高糖诱导的肾纤维化和炎症。

BMC Complement Altern Med. 2019 Jan 10;19(1):14. doi: 10.1186/s12906-018-2410-7.

Exploring macrophage cell therapy on Diabetic Kidney Disease.探讨巨噬细胞细胞疗法在糖尿病肾病中的应用。

J Cell Mol Med. 2019 Feb;23(2):841-851. doi: 10.1111/jcmm.13983. Epub 2018 Nov 8.

The protective effect of human renal sinus fat on glomerular cells is reversed by the hepatokine fetuin-A.人肾窦脂肪对肾小球细胞的保护作用被肝细胞因子胎球蛋白 A 逆转。

Sci Rep. 2017 May 23;7(1):2261. doi: 10.1038/s41598-017-02210-4.

C-C motif-ligand 2 inhibition with emapticap pegol (NOX-E36) in type 2 diabetic patients with albuminuria.在患有蛋白尿的2型糖尿病患者中使用依马卡普聚乙二醇（NOX-E36）抑制C-C基序配体2

Nephrol Dial Transplant. 2017 Feb 1;32(2):307-315. doi: 10.1093/ndt/gfv459.

Macrophage in chronic kidney disease.慢性肾病中的巨噬细胞。

Clin Kidney J. 2016 Dec;9(6):765-771. doi: 10.1093/ckj/sfw096. Epub 2016 Oct 5.

Innate immunity in diabetes and diabetic nephropathy.糖尿病和糖尿病肾病中的固有免疫。

Nat Rev Nephrol. 2016 Jan;12(1):13-26. doi: 10.1038/nrneph.2015.175. Epub 2015 Nov 16.

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验