Agladioglu Kadir, Pekel Gökhan, Citisli Veli, Yagci Ramazan
Department of Radiology, Pamukkale University, Denizli, Turkey.
Department of Ophthalmology, Pamukkale University, Denizli, Turkey.
J Clin Ultrasound. 2015 Nov-Dec;43(9):567-72. doi: 10.1002/jcu.22269. Epub 2015 Mar 20.
Decreased retinal arteriolar caliber and increased retinal venular caliber have been associated with increased cardiovascular mortality. This study aimed to evaluate correlations of choroidal thickness and retinal vascular caliber measurements with internal carotid artery (ICA) Doppler ultrasound variables.
In this cross-sectional and observational study, 43 eyes and ICAs of 43 healthy volunteers were examined. Spectral domain optical coherence tomography was used to measure subfoveal choroidal thickness (SFCT) and retinal vascular caliber. The ICA Doppler ultrasonographic parameters were diameter, flow volume, peak-systolic velocity, end-diastolic velocity, resistance index (RI), and pulsatility index (PI).
Negative correlations emerged between ICA RI and SFCT (p = 0.017, r = -0.36) as well as between ICA PI and retinal arteriolar caliber (p = 0.015, r = -0.37). A negative linear correlation appeared between ICA diameter and SFCT (p = 0.005, r = -0.42), although ICA diameter and flow volume showed no association with retinal vessel caliber (p > 0.05).
Choroidal thickness is negatively correlated with ICA diameter and ICA RI, while retinal arteriolar caliber is inversely related with ICA PI in normal volunteers.
视网膜小动脉管径减小和视网膜小静脉管径增大与心血管死亡率增加有关。本研究旨在评估脉络膜厚度和视网膜血管管径测量值与颈内动脉（ICA）多普勒超声变量之间的相关性。
在这项横断面观察性研究中，对43名健康志愿者的43只眼睛和颈内动脉进行了检查。使用光谱域光学相干断层扫描测量黄斑中心凹下脉络膜厚度（SFCT）和视网膜血管管径。颈内动脉多普勒超声参数包括直径、血流量、收缩期峰值流速、舒张末期流速、阻力指数（RI）和搏动指数（PI）。
颈内动脉RI与SFCT之间呈负相关（p = 0.017，r = -0.36），颈内动脉PI与视网膜小动脉管径之间也呈负相关（p = 0.015，r = -0.37）。颈内动脉直径与SFCT之间呈负线性相关（p = 0.005，r = -0.42），尽管颈内动脉直径和血流量与视网膜血管管径无相关性（p > 0.05）。
在正常志愿者中，脉络膜厚度与颈内动脉直径和颈内动脉RI呈负相关，而视网膜小动脉管径与颈内动脉PI呈负相关。
