Meldrum Suzanne, Dunstan Janet A, Foster Jonathan K, Simmer Karen, Prescott Susan L
Centre for Neonatal Research and Education, School of Paediatrics and Child Health, Faculty of Medicine, Dentistry and Health Sciences, University of Western Australia, Crawley 6009, Australia.
School of Psychology and Social Science, Faculty of Health, Engineering and Science, Edith Cowan University, Joondalup 6027, Australia.
Nutrients. 2015 Mar 20;7(3):2061-7. doi: 10.3390/nu7032061.
A number of trials have been undertaken to assess whether the intake of omega-3 long-chain polyunsaturated fatty acids (n-3 LCPUFA) during pregnancy can influence the neurological development of the offspring, yet no consensus from these trials has been reached. We aimed to investigate the long-term effects (12 years) of fish oil supplementation in pregnancy on neurodevelopment, including cognition, language and fine motor skills. In a follow up of a previously published randomised controlled trial of 98 pregnant women, their children were assessed at 12 years of age using a battery of neurodevelopmental assessments. Fifty participants were assessed at 12 years, with 25 participant's mothers receiving fish oil supplementation, and 25 receiving control capsules. There were no significant differences for any of the assessment measures completed. Our data indicate that fish oil supplementation during pregnancy does not influence the cognition, language or fine motor skills of children in late primary school (12 years of age).
已经进行了多项试验来评估孕期摄入ω-3长链多不饱和脂肪酸（n-3 LCPUFA）是否会影响后代的神经发育，但这些试验尚未达成共识。我们旨在研究孕期补充鱼油对神经发育的长期影响（12年），包括认知、语言和精细运动技能。在对之前发表的一项针对98名孕妇的随机对照试验进行随访时，使用一系列神经发育评估方法对她们的孩子在12岁时进行了评估。12岁时对50名参与者进行了评估，其中25名参与者的母亲接受了鱼油补充，25名接受了对照胶囊。完成的任何评估指标均无显著差异。我们的数据表明，孕期补充鱼油不会影响小学后期（12岁）儿童的认知、语言或精细运动技能。
