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Drosophila nervous system as a target of aging and anti-aging interventions.

作者信息

Omelyanchuk Leonid V, Shaposhnikov Mikhail V, Moskalev Alexey A

机构信息

Institute of Molecular and Cellular Biology, Siberian Branch of Russian Academy of Sciences Novosibirsk, Russia ; Department of Cytology and Genetics, Novosibirsk State University Novosibirsk, Russia.

Institute of Biology of Komi Science Center of Ural Branch of Russian Academy of Sciences Syktyvkar, Russia ; Moscow Institute of Physics and Technology Dolgoprudny, Russia.

出版信息

Front Genet. 2015 Mar 10;6:89. doi: 10.3389/fgene.2015.00089. eCollection 2015.

DOI:10.3389/fgene.2015.00089
PMID:25806047
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4354387/
Abstract
摘要

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本文引用的文献

1
Gadd45 expression correlates with age dependent neurodegeneration in Drosophila melanogaster.Gadd45的表达与黑腹果蝇中年龄依赖性神经退行性变相关。
Biogerontology. 2015 Feb;16(1):53-61. doi: 10.1007/s10522-014-9533-0. Epub 2014 Sep 25.
2
Brain aging, memory impairment and oxidative stress: a study in Drosophila melanogaster.大脑衰老、记忆损伤与氧化应激：一项针对黑腹果蝇的研究
Behav Brain Res. 2014 Feb 1;259:60-9. doi: 10.1016/j.bbr.2013.10.036. Epub 2013 Oct 30.
3
A pharmacological network for lifespan extension in Caenorhabditis elegans.秀丽隐杆线虫中延长寿命的药理学网络。
Aging Cell. 2014 Apr;13(2):206-15. doi: 10.1111/acel.12163. Epub 2013 Nov 13.
4
Increased expression of Drosophila Sir2 extends life span in a dose-dependent manner.果蝇Sir2表达的增加以剂量依赖的方式延长寿命。
Aging (Albany NY). 2013 Sep;5(9):682-91. doi: 10.18632/aging.100599.
5
The role of the nervous system in aging and longevity.神经系统在衰老和长寿中的作用。
Front Genet. 2013 Jun 27;4:124. doi: 10.3389/fgene.2013.00124. Print 2013.
6
Neuronal inputs and outputs of aging and longevity.衰老和长寿的神经元输入和输出。
Front Genet. 2013 May 6;4:71. doi: 10.3389/fgene.2013.00071. eCollection 2013.
7
Misexpression screen delineates novel genes controlling Drosophila lifespan.基因表达谱筛选揭示控制果蝇寿命的新基因。
Mech Ageing Dev. 2012 May;133(5):234-45. doi: 10.1016/j.mad.2012.02.001. Epub 2012 Feb 24.
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Increased transsulfuration mediates longevity and dietary restriction in Drosophila.转硫作用增加介导果蝇的长寿和饮食限制。
Proc Natl Acad Sci U S A. 2011 Oct 4;108(40):16831-6. doi: 10.1073/pnas.1102008108. Epub 2011 Sep 19.
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A gain-of-function screen identifies wdb and lkb1 as lifespan-extending genes in Drosophila.一项功能获得性筛选鉴定出 wdb 和 lkb1 是果蝇寿命延长的基因。
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Increase of Drosophila melanogaster lifespan due to D-GADD45 overexpression in the nervous system.由于 D-GADD45 在神经系统中的过度表达，导致果蝇寿命延长。
Biogerontology. 2011 Jun;12(3):211-26. doi: 10.1007/s10522-010-9311-6. Epub 2010 Dec 9.