Ekiz Özlem, Rifaioǧlu Emine Nur, Şen Bilge Bülbül, Çulha Gülnaz, Özgür Tümay, Doǧramaci Asena Çiǧdem
Department of Dermatology, Mustafa Kemal University School of Medicine, Hatay, Turkey.
Department of Parasitology, Mustafa Kemal University School of Medicine, Hatay, Turkey.
Indian J Dermatol. 2015 Mar-Apr;60(2):216. doi: 10.4103/0019-5154.152576.
Leishmaniasis recidiva cutis (LRC) is an unusual form of acute cutaneous leishmaniasis. Herein, we present a case of LRC of the lips mimicking granulomatous cheilitis. An 8-year-old, Syrian child admitted with a swelling and disfigurement of his lips for 4 years. Abundant intra and extracellular Leishmania amastigotes were determined in the smear prepared from the lesion with Giemsa stain. Histopathology showed foamy histiocytes and leishmania parasites within the cytoplasm of macrophages in the epidermis and a dense dermal mixed type inflammatory cell infiltrate composed of lymphocytes, foamy histiocytes with multinucleated giant cells. On the basis of anamnestic data, the skin smears results, clinical and histopathologic findings, LRC was diagnosed. The patient was treated with meglumine antimoniate intramuscularly and fluconazole orally. Cryotherapy was applied to the residual papular lesions. The lesion improved markedly at the first month of the treatment.
皮肤利什曼病复发型（LRC）是一种不常见的急性皮肤利什曼病形式。在此，我们报告一例疑似肉芽肿性唇炎的唇部LRC病例。一名8岁叙利亚儿童因唇部肿胀和畸形入院，病程4年。用吉姆萨染色法对病变部位制备的涂片进行检查，发现大量细胞内和细胞外利什曼无鞭毛体。组织病理学显示，表皮巨噬细胞胞质内有泡沫状组织细胞和利什曼原虫寄生虫，真皮有由淋巴细胞、泡沫状组织细胞和多核巨细胞组成的密集混合性炎症细胞浸润。根据既往病史、皮肤涂片结果、临床和组织病理学表现，诊断为LRC。患者接受了葡甲胺锑肌内注射和氟康唑口服治疗。对残留的丘疹性病变进行了冷冻治疗。治疗第一个月病变明显改善。
