轮班工作与血压关系的多中心历史性队列研究
Multicenter historical cohort study of the relationship between shift work and blood pressure.
作者信息
Gholami-Fesharaki Mohammad, Kazemnejad Anoshirvan, Zayeri Farid, Rowzati Mohsen, Sanati Javad, Akbari Hamed
机构信息
Assistant Professor, Department of Biostatistics, School of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
Professor, Department of Biostatistics, School of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
出版信息
ARYA Atheroscler. 2014 Nov;10(6):287-91.
BACKGROUND
Regarding the relationship between blood pressure (BP) and shift work (SW), previous studies have reported contradictory results. In the present study, we used Bayesian multilevel modeling to evaluate the association of SW and BP after controlling some confounding factors.
METHODS
Data of this multicenter historical study were extracted from annual observations of the male workers of Isfahan's Mobarakeh Steel Company (IMSC) and Polyacryl Iran Corporation (PIC) in Isfahan, Iran, between 2003 and 2011. In this research, we assessed the effect of SW on systolic BP (SBP) and diastolic BP (DPB) with controlling body mass index, age, work experience, marriage, and education status.
RESULTS
A total of 8613 (IMSC, n = 5314 and PIC, n = 3299) workers participated in this study with a mean [standard deviation (SD)] age of 41.60 (8.30) and mean (SD) work experience of 16.17 (7.89) years. In this study, after controlling confounding factors, we found no significant relationship between SW and SBP and DBP.
CONCLUSION
In general, the results of this multicenter cohort study did not support a relationship between SW and BP. We suggest prospective studies with controlling more confounding factors in this area.
背景
关于血压（BP）与轮班工作（SW）之间的关系，以往的研究报告了相互矛盾的结果。在本研究中，我们使用贝叶斯多层次模型来评估在控制一些混杂因素后轮班工作与血压之间的关联。
方法
这项多中心历史研究的数据提取自2003年至2011年期间伊朗伊斯法罕的莫巴拉克钢铁公司（IMSC）和伊朗聚丙烯公司（PIC）男性工人的年度观察数据。在本研究中，我们在控制体重指数、年龄、工作经验、婚姻状况和教育程度的情况下，评估了轮班工作对收缩压（SBP）和舒张压（DBP）的影响。
结果
共有8613名（IMSC，n = 5314；PIC，n = 3299）工人参与了本研究，平均[标准差（SD）]年龄为41.60（8.30）岁，平均（SD）工作经验为16.17（7.89）年。在本研究中，在控制混杂因素后，我们发现轮班工作与收缩压和舒张压之间没有显著关系。
结论
总体而言，这项多中心队列研究的结果不支持轮班工作与血压之间存在关联。我们建议在该领域进行控制更多混杂因素的前瞻性研究。
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